RESUMEN
Objective This study investigated the relation with the location of infarction and brain natriuretic peptide (BNP),left ventricular ejection fraction (LVEF) for first acute ST-segment elevation myocardial infarction.Methods From January 2014 to December 2016,163 consecutive patients with ASTEMI who admitted to our hospital were enrolled in this study,were divided by infarction position.All the patients were classified into wide anterior infarction group,anterior infarction group,anterior septal infarction group and inferior infarction group.The BNP level and the LVEF were measured for 163 consecutive patients respectively on admission and after six-month follow-up visit and record the adverse cardiovascular events,comparing their relations.Results The BNP level of wide anterior infarction group were all significantly higher than all the other groups on admission and after six-month follow-up visit,but the LVEF were significantly lower than all the other groups (P ＜ 0.05).The BNP level of anterior infarction group were significantly higher than anterior septal infarction group and inferior infarction group on admission and after six-month follow-up visit,but the LVEF were significantly lower than anterior septal infarction group and inferior infarction group (P ＜ 0.05).The BNP level of anterior septal infarction group were higher than inferior infarction group on admission and after six-month follow-up visit,but the LVEF were lower than inferior infarction group (P ＜ 0.05).Meanwhile,the incidence of adverse cardiovascular events of the wide anterior infarction group,anterior infarction group,anterior septal infarction group were all larger than inferior infarction group,and the wide anterior infarction group was the largest.Conclusion There is a close relationship with infarction position,BNP and LVEF.The location of infarction,BNP level and LVEF counld all be recognized as the important predicted indicator of adverse cardiovascular events,premature complication and prognosis.
RESUMEN
Objective : To study plasma N terminal pro brain natriuretic peptide (NT-proBNP ) level difference be-tween Han nationality and Uighur nationality patients with acute coronary syndrome (ACS) in Xinjiang .Methods : A total of 482 Uygur and Han nationalities ACS patients (uighur : 212 cases , han : 270 cases) hospitalized from May 2012 to Aug 2013 were selected . According to ACS types , they were divided into unstable angina pectoris (UAP) group (n = 234) ,acute ST segment elevation myocardial infarction (STEMI) group (n = 166) and acute non- ST segment elevation myocardial infarction (NSTEMI) group (n = 82) .All patients received coronary angiography (CAG) and their NT-proBNP levels were compared .Results : ① CAG results indicated that Uygur nationality ACS patients were mainly multi-vessel coronary disease and the percentage was significantly higher than that of Han na - tionality ACS patients (61.32% vs .40.00% ) ; ② Compared with Han nationality ACS patients ,there were significant rise in NT-proBNP levels [UAP : 168.5 (70.6 ~ 272.5) pg/ml vs .383.2 (210.3 ~ 739.5 ) pg/ml ,STEMI : 618.5 (231.7 ~ 1387) pg/ml vs .1209.5 (908 ~ 3214) pg/ml ,NSTEMI : 446.7 (252.21 ~ 831.92) pg/ml vs .1066 (928 ~ 3448.25) pg/ml] in Uygur nationality ACS patients ; ③ Compared with Han nationality ACS patients ,there were significant rise in NT-proBNP levels [Single vessel : 221.7 (20 ~ 2851) pg/ml vs .557.1 (125 ~ 1956.2) pg/ ml ,double-vessel : 421.2 (75.2 ~ 3401.5) pg/ml vs .610.5 (174.4 ~ 5679.1) pg/ml ,multi-vessel : 648.2 (142.4 ~ 3850) pg/ml vs .812.3 (154.8 ~ 6832.5) pg/ml] in Uygur nationality patients with different number of diseased coronary vessels , P < 0.05 ~ < 0.01 .Conclusion : NT-proBNP level in Uygur nationality ACS patients is significant - ly higher than that of Han nationality patients ,it may be related with hereditas ,living habit ,risk factor control , early diagnosis and treatment of disease ,post-discharge compliance of treatment ,which possesses important value for assessing patient′s condition .