RESUMEN
Serum calcium has been estimated among 16 controls and compared with that from patients, using three methods, Cresophthalin complex method and Trender method and Permanganate titration method, Cresophthalin complex method is considered to be the best method for the determination of serum calcium, because of it's specificity and accuracy. The evaluation of serum calcium among patients showed, that 15 are normocalcemic, 20 patients are hypocalcemia and 15 patients are with hyperalcemia. From cases of hypercalcemia, 8 patients had malignancy, [5 with metastasis to bones, 3 were without metastasis to bones]. 3 patients had Multiple Myeloma. Where as the other 3 patients had primary hyperparathyroidism and another patient had hypercalcemia due to over use of vitamin D