RESUMEN
Objectives: To assess and compare the effect of commonly prescribed pediatric syrup formulations on primary tooth enamel hardness over a period of 7 days. Materials and Methods: An in vitro study was done on 40 noncarious deciduous molar teeth. 10 teeth in each group were dipped in 4 pediatric syrups (Amoxicillin, Metronidazole, Paracetamol,Ibuprufen + paracetamol) for 1 min thrice daily for 7days and the enamel surface micro-hardness was checked at baseline and at the end of 7th day by Vickers hardness testing machine. Results: ANOVA test indicated that the reduction in mean micro hardness at the end of 7th day was maximum in Group A(Amoxicillin) and least in Group D(Ibugesic + Paracetamol).Conclusion: Pediatric liquid medicines can cause dental erosion and have a hazardous effect on the enamel hardness.