Conservative surgery in patients with malignant ovarian germ cell tumours

Conservative surgery with adjuvant chemotherapy has made the preservation of fertility even in patient with advanced disease. The increase in cure rate has shifted to research for the long term menstrual reproductive and gynecologic outcome in these patients. The current study is retrospective for 25 cases of ovarian malignant germ cell tumor from January 2006 to January 2011, at El Hussian and Sayed Galal University Hospitals. The uterus and contralateral ovary were retained to preserve ovarian function with or without chemotherapy, followed up for two years. The mean age of most patients ranged from 15-28 years [average 21.5 years]. According to International Federation of Gynecology and Obstetrics, the histological subtypes were ten dysgerminoma [40%]. Five immature teratoma [20%], three endodermal sinus tumor [12%], four mixed germ cell tumor [16%] three embryonic cell tumours [12%]. Stage I: tumors 15 cases [60%], Stage II: tumors one case [4%], Stage III tumors 6 cases [24%], Stage IV tumors 3 cases [12%]. Adjuvant chemotherapy was administered to 15 cases 60% and followed up for two years. There were two recurrences, one died at 7[th] day postoperative of massive pulmonary embolism with past history of D.V.T, five healthy live births in the chemotherapy group without birth defects, and one infertility case 4%

Quality of life after breast carcinoma surgery in women with operable breast cancer a comparison of three surgical procedures

Because breast conservative surgery [BCS], mastectomy alone, mastectomy with reconstruction is equally effective for treatment of early stage of breast carcinoma. Now choice of women focus on quality of life, psychosocial results and individual response following breast carcinoma surgery. The involved women in this study aged between 30:85 years [median 57.5] with newly diagnosed breast carcinoma who underwent BCS [n=25]. Mastectomy alone [n=15], Mastectomy with reconstruction [n=10]. The quality of life was assessed after diagnosis [baseline] and at 1,3,6,12,18 and 24 months after baseline by using mischel uncertainly in illness scale [MUIS], profile for mood states [POTIS] and functional assessment of cancer therapy for breast cancer [FACT-B] Women who underwent mastectomy with reconstruction had greater mood disturbance and poorer well being than women who had mastectomy alone, women who underwent BCS had more mood disturbances than women who had mastectomy alone. As regarding well being BCS and mastectomy did not differ significantly. With regard quality of life is not better in women with BCS or mastectomy with reconstruction than in women with mastectomy alone. Mastectomy with reconstruction is associated with greater mood disturbance and poorer well being

Clinical studies on cutaneous leishmaniasis in Saudi Arabia

Cutaneous Leishmaniasis is an endemic disease in the Middle East. In Saudi Arabia, the disease constitutes a major problem to dermatologists, especially in the Middle region of the Kingdom. A total of 27 human cases of cutaneous Leishmaniasis were studies. Positive cases were treated and followed up. Most of the interesting cases were photographed. The whole results were discussed on the light of other work previously done