Cerebral vein thrombosis in women using short course oral contraceptive consumption

Muslim women tend to postpone their menstrual period using short course oral contraceptives [OC] during Ramadan, Muslims fasting month. Recently, many cases of stroke, particularly cerebral vein thrombosis [CVT], have been reported in Ramadan. This work studies the incidence of CVT and its relation to Ramadan. This is a cohort study conducted from October 2006 to October 2009 and included 4 consecutive Ramadan's. All patients with definite diagnosis of CVT who were referred to the neurology department of Ghaem Hospital, Mashhad, Iran in this four-year period were included in the study. During the study period, 70 cases with CVT [11 males and 59 females] were recruited. Twenty five cases were admitted during Ramadan months which was significantly higher than all the other 32 months [p=1.9×10[-7]]. The higher frequency of females [6 times more] among CVT cases probed by investigating possible risk factors and short term OC consumption was revealed as the major risk factor [p=0.00071]. Higher incidence of CVT in females during Ramadan suggests the presence of specific risk factors in this group. Our study revealed that short-term use of OCs may be a major risk factor for CVT

investigation into the CSFabsorption in cats

Cerebrospinal fluid [CSF], its secretion, circulation and absorption have been the subject of recent researches. There is a general agreement that the main site of CSF secretion is in the choroids plexus. However, the main absorption site is controversial. Some believe that arachnoid granulations are the principle sites of CSF absorption. In this study, different locations of CSF absorption in cats are investigated. 2 ml [100 mg], of ferrous dextran was injected into the subarachnoid compartment of seven cats. After 15 days the animals were euthanized, and the central nervous system [CNS] and its relative tissues were analyzed for any iron amlumulation. Several tissue samples were taken and stained with Prussian blue and Hernatoxylin-eosin. The light microscopic study of different tissues showed amlumulation of the tracer in olfactory and optic nerves, dorsal root ganglia as well as spinal nerve roots. The main locations of CSF absorption were the spinal nerve roots and their surrounding lymphatic tissue. There is reason to believe that some endothelial fenestrate within these roots were involved in this process