Oral health and coronary artery disease, a review article

Atherosclerosis is the most common cause of myocardial infarction and ischemic stroke. Various risk factors have been identified for atherosclerosis. Recently, bacterial and viral organisms, which are involved in chronic inflammatory processes, have been also implicated in atherosclerosis development. Individuals with a prior history of periodontal diseases and/or tooth loss are considered to be at a higher risk for peripheral arterial disease, compared to those without periodontal diseases or tooth loss. Evidence suggests that periodontitis contributes to the overall burden of infection and inflammation and may lead to cardiovascular events and stroke in susceptible patients. In this article, we aimed to review the available data on the relationship between periodontal diseases and cardiovascular diseases, especially coronary artery disease. At least sixty papers were reviewed during 2014-15. Of these, 44 were included in our study

[Comparison of the effects of eight-week endurance training, resistance and garlic extract supplementation on MDA and TAC in rats with metabolic syndrome]

Background and Objectives: In accordance with the limited studies on the effects of eendurance [ET] and resistance [RT] training with and without the garlic extract [GE] on metabolic syndrome, this study was conducted to identify and compare the effects of eight-weeks ET, RT and GE supplementation on malondialdehyde [MDA] and total antioxidant capacity [TAC] in rats with metabolic syndrome

Materials and Methods: 48 rats with metabolic syndrome [12-weeks, weight range of 310 to 350 g] in a randomized design were allocated into six equal groups: control [n=8], ET [n=8], RT [n=8], ET+GE [n=8], RT+GE [n=8], GE [500mg/kg, n=8]. After familiarization of the rats with metabolic syndrome, 8-weeks [3 sessions a week] in an exercise protocol [ET, RT] with or without GE. Data were analyzed using one-way ANOVA and Bonferroni [Sig<0.05]

Results: The results show that ET and RT with GE consumption have significant effect on stress oxidative indices [TAC and MDA]

Conclusion: Endurance and resistance training along with GE consumption can increase the TAC base, reduce unfavorable changes in serum MDA syndrome

[Effect of coenzyme Q10 supplementation on exercise response in some hematological parameters in non-athletes men]

Background and Objectives: There is limited available data about the effects of antioxidant supplements on changes of hematological parameters after exercise. This study was carried out to investigate the effect of short-term CoenzymeQ10 supplementation on white blood cells, hemoglobin and red blood cell indices in non-athlete men after relatively intense running

Materials and Methods: Twenty healthy inactive men [25+/-3 years, fat 13+/-2. % and VO2max 41+/-2 ml/kg/min] in a randomized and double-blind design were allocated in two equal groups: supplement [2.5 mg/kg/day Coenzyme Q10] and placebo [2.5 mg/kg/day dextrose] groups. After the 14-day supplementation therapy, all subjects were participated in an aerobic exercise with 75% VO2max on the treadmill for 30 minutes. Blood samples obtained before the Q10 supplementation along with before and after the exercise protocol

Results: Ingestion 14-day coenzymQ10 supplementation on indexs [RBC, Hg, MCV, MCH, MCHC, Hct, WBC,PLT, lanphosit percentages, notrophils and other blood cells] had no significant effect [P>0.05] on basal parameters. Moreover, aerobic exercise causes lower red blood cells counts, hemoglobin and hematocrit and increase White blood cells and platelete [P<0.05], However, the rang of lower red blood cells, hemoglobin, hematocrit and increase white blood cells in supplementation group after aerobic exercise low was that placebo group [P<0.05]

Conclusion: Tngestion 14-day coenzymQ10 supplementation [with 2/5 g/kg/day] in effective on withe blood cells, hemoglobin and red blood cell indices after that aerobic exercise

Device-induced perforation of right atrium following interventional closure of atrial septal defect [ASD]

This is a case presentation of a 26-year-old woman with a moderate-sized atrial septal secundum defect [17mm] who underwent catheterism, during which an Amplatzer Septal Occluder number 26 was inserted successfully. On the second postoperative day, she deteriorated and a clinical examination showed a typical tamponade. After a percutaneous aspiration of the pericardial cavity and transient improvement in vital signs, a pig-tail catheter was inserted percutaneously emergently, and the patient was transferred to the operating room in a preshock state. During the operation, an active bleeding point in the superoanterior aspect of the right atrium near the aortic root was detected, which was repaired by direct suture and pericardial patch reinforcement. The Amplatzer device was removed and the atrial septal defect was repaired with a pericardial patch. A lethal complication of the interventional closure of atrial septal defect, properly treated by an emergent intervention and operation, is presented and discussed herein

Modified Blalock-Taussig shunt and giant perigraft reaction

This is a case of a modified Blalock-Taussig shunt, which was complicated by perigraft transudative, fibrinous fluid accumulation and recurrence after surgical intervention. Follow-up and expectant management of the patient was successful. Our experience regarding this complication is presented