Alpha-glutathione S-transferase and serum aminotransferases in Schistosomiasis mansoni patients with or without hepatitis C virus

The present study evaluated delta-Glutathione-S-transferase as a biochemical marker for hepatocellular damage in schistosomiasis mansoni patients, with or without chronic hepatitis C [HCV] patients as compared to controls. Alpha GST, ALT and AST were assayed in sera of GI: 20 schistosomiasis mansoni patients with HCV, GII 16 schistosomiasis mansoni patients without HCV, GIII 19 pure HCV patients and GIV: 20 normal controls. The results showed that delta-Glutathione-S-transf erase was less sensitive and less specific but more accurate than ALT and AST as a liver affection marker in HCV patients