RESUMEN
The aim of this study was to conduct a sero-epidemiological survey of toxoplasmosis in pregnant Sudanese women. Four hundred and eighty-seven pregnant women attending antenatal clinics in Khartoum and Omdurman, Maternity Hospitals, Sudan during the period June through to December 2000 were counselled for socio-demographic and obstetrical risk factors for toxoplasmosis, and screened for immunoglobin G [IgG] and IgM anti-toxoplasma antibodies using enzyme linked immunoassay. Immunoglobin G anti-toxoplasma antibodies were positive [titre > 11 IU/ml] in 166/487 [34.1%], while 321/487[65.9%] were sero-negative. The sera of 35 women showed very high titres [>100 IU/ml], 5/35 [14.3%] were IgM-positive. The risk factors for IgG anti-toxoplasma seropositivity were; Southern ethnic origin and consumption of raw meat. Thirty [18.1%] out of 166 women who were IgG anti-toxoplasma seropositive gave history of intrauterine fetal death, while 31 [9.7%] out of 321 women who were sero-negative gave history of intrauterine fetal death, the difference was statistically significant [P < 0.05]. Over 65% Sudanese women screened for anti-toxoplasma IgG antibodies were sero-negative and they were at risk of sero-conversion during pregnancy. Southers and eating raw meat were the risk factors for toxoplasmosis in Sudanese pregnant women