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1.
Indian J Exp Biol ; 2002 Jul; 40(7): 791-5
Artículo en Inglés | IMSEAR | ID: sea-62045

RESUMEN

Dried leaf powder of mulberry (M. indica L.) when given along with the diet at 25% level to streptozotocin induced diabetic male Wistar albino rats for 8 weeks, controlled hyperglycemia, glycosuria, albuminuria and retarded onset of retinopathy. Untreated diabetic rats showed hyperglycemia, glycosuria, albuminuria and developed lenticular opacity after 8 weeks of experimental period.


Asunto(s)
Animales , Catarata/complicaciones , Diabetes Mellitus Experimental/complicaciones , Hemoglobina Glucada/análisis , Hiperglucemia/complicaciones , Hipoglucemiantes/uso terapéutico , Masculino , Morus/química , Extractos Vegetales/uso terapéutico , Hojas de la Planta/química , Ratas , Ratas Wistar , Estreptozocina
2.
Indian J Exp Biol ; 2000 Jun; 38(6): 607-9
Artículo en Inglés | IMSEAR | ID: sea-56698

RESUMEN

Hypoglycemic, diuretic and hypocholesterolemic effects of roots of W. somnifera (ashvagandha) were assessed on human subjects. Six mild NIDDM subjects and six mild hypercholesterolemic subjects were treated with the powder of roots of W. somnifera for 30 days. Suitable parameters were studied in the blood and urine samples of the subjects along with dietary pattern before and at the end of treatment period. Decrease in blood glucose was comparable to that of an oral hypoglycemic drug. Significant increase in urine sodium, urine volume, significant decrease in serum cholesterol, triglycerides, LDL (low density lipoproteins) and VLDL (very low density lipoproteins) cholesterol were observed indicating that root of W. somnifera is a potential source of hypoglycemic, diuretic and hypocholesterolemic agents. Clinical observations revealed no adverse effects.


Asunto(s)
Adulto , Anticolesterolemiantes/efectos adversos , Glucemia/análisis , Cápsulas , Diabetes Mellitus Tipo 2/tratamiento farmacológico , Diuresis/efectos de los fármacos , Diuréticos/efectos adversos , Humanos , Hipercolesterolemia/tratamiento farmacológico , Hipoglucemiantes/efectos adversos , Lípidos/sangre , Persona de Mediana Edad , Natriuresis/efectos de los fármacos , Extractos Vegetales/efectos adversos , Raíces de Plantas/química , Plantas Medicinales/química , Potasio/análisis , Polvos , Sodio/análisis , Solanaceae/química
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