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2.
J Postgrad Med ; 1992 Apr-Jun; 38(2): 55-7
Artículo en Inglés | IMSEAR | ID: sea-117750

RESUMEN

Fifty patients of either sex, aged between 20 and 60 years undergoing electroconvulsive therapy were included in our study. Each patient was used as his/her own control. We observed the cardiovascular changes without nitroglycerin ointment in the first sitting and in the next sitting with the application of 2 inches of 2% nitroglycerin ointment 45 min before the electroconvulsive therapy. Arterial blood pressure and heart rate increase during electroconvulsive therapy can be effectively attenuated by application of 2 inches of 2% nitroglycerin ointment 45 min before the electroconvulsive therapy (p < 0.001 and p < 0.01 resp.). This may be especially beneficial for patients who are at increased risk of myocardial ischemia and stroke.


Asunto(s)
Adulto , Presión Sanguínea/efectos de los fármacos , Terapia Electroconvulsiva/efectos adversos , Femenino , Frecuencia Cardíaca/efectos de los fármacos , Humanos , Hipertensión/tratamiento farmacológico , Masculino , Persona de Mediana Edad , Nitroglicerina/administración & dosificación , Pomadas
3.
J Postgrad Med ; 1989 Jan; 35(1): 3-8
Artículo en Inglés | IMSEAR | ID: sea-117542

RESUMEN

Twenty-nine acute schizophrenic patients were treated under double-blind conditions for six weeks with either centbutindole in a dose range of 3 mg/day to 4.5 mg/day or trifluoperazine in the dose range of 15 mg/day to 22.5 mg/day. Both drugs produced a significant improvement in initial psychopathology. No significant differences were demonstrated between the two treatment conditions.


Asunto(s)
Adulto , Ensayos Clínicos como Asunto , Método Doble Ciego , Femenino , Humanos , Masculino , Pirazinas/efectos adversos , Distribución Aleatoria , Esquizofrenia/diagnóstico , Trifluoperazina/efectos adversos
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