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Mem. Inst. Oswaldo Cruz ; 100(7): 765-769, Nov. 2005. ilus, tab
Artículo en Inglés | LILACS | ID: lil-419704

RESUMEN

Indirect enzyme-linked immunosorbent assays (ELISAs) based on recombinant MSP1a and MSP2 from a Brazilian isolate of Anaplasma marginale were developed to detect antibodies against this rickettsia in cattle. The high sensitivities (99 percent for both tests) and specificities (100 percent for both tests) were confirmed with sera from cattle positive or negative for A. marginale antibodies, respectively, by immunofluorescent antibody test. By the analysis of 583 sera from cattle of three regions of the state of Pernambuco, Brazil, the agreement between both tests was high, with a kappa index of 0.89. The similar performances of the ELISAs suggest that both tests can be used in epidemiological surveys for detection of antibodies to A. marginale in cattle.


Asunto(s)
Bovinos , Animales , Anaplasma marginale/inmunología , Anaplasmosis/diagnóstico , Anticuerpos Antibacterianos/sangre , Antígenos Bacterianos/inmunología , Proteínas de la Membrana Bacteriana Externa/inmunología , Enfermedades de los Bovinos/diagnóstico , Ensayo de Inmunoadsorción Enzimática/veterinaria , Antígenos Bacterianos/genética , Proteínas de la Membrana Bacteriana Externa/genética , Enfermedades de los Bovinos/microbiología , Técnica del Anticuerpo Fluorescente , Proteínas Recombinantes/genética , Proteínas Recombinantes/inmunología , Sensibilidad y Especificidad
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