Case Report Of Mucha-Habermann Disease

Pityriasis lichenoides et varioliformis acuta (PLEVA), also known as a Mucha-Habermann disease, is an uncommon, idiopathic, and acquired dermatosis. The disease is characterized by erythematous, scaly, papules, and polymorphic lesions which often progresses to hemorrhagic necrosis and heals with varioliform scarring. A febrile ulceronecrotic variant of PLEVA, also termed pityriasis lichenoides (PL) with ulceronecrosis and hyperthermia (PLUH) or febrile ulceronecrotic Mucha-Habermann disease (FUMHD), is a severe variant of PLEVA. The disease is characterized by the acute onset of large, more destructive, coalescent papules, leading to ulceronecrotic skin lesions associated with high fever and other systemic symptoms. In spite of the presence of multiple treatment modalities with variable success rate, the disease has poor prognosis. Here, we report the case of a 17-year-old male patient who presented with typical features of FUMHD and responded well to systemic administration of corticosteroid therapy.

Antioxidant and Anti Cholinesterase Potential of Red Cabbage (Brassica oleracea var. capitata f. rubra)

Aim: This study aims at in-vitro evaluation of Red cabbage extracts for their antioxidant and anticholinesterase activity. Methodology: Red cabbage collected from the local market was dried and extracted with different solvents. Qualitative and quantitative phytochemical screening of these extracts was done. Then the Resulting extracts were evaluated for antioxidant activity using DPPH and H2O2 scavenging at various concentrations. Anticholinesterase activity was assessed qualitatively using TLC autobiography. Conclusions: Maximum antioxidant activity was found with methanolic extract and Maximum anticholinesterase activity is found with Hexane extract.

Comparative assessment of intelligence quotient among children living in high and low fluoride areas of Kutch, India- a pilot study

Long-term ingestion of large amounts of fluoride can lead to potentially severe skeletal problems and neurological consequences. The study was conducted to assess and compare intelligence quotient of children living in high and low fluoride areas in Kutch, Gujarat, India. A cross-sectional descriptive survey was conducted among 100 school children aged 8 to 10 years, living in Kutch District, Gujarat, India during July 2012. Mundra [2.4 to 3.5 mg/L] and Bhuj [0.5mg/L] were the two villages randomly selected to represent the high and low water fluoride areas respectively. Seguin Form Board Test was used to assess the intelligence quotient [IQ] level of children. Descriptive statistics and independent sample t-test was used for analysis. Mean scores for average, shortest and total timing category were found to be significantly higher [P<0.05] among children living in Mundra [30.45 +/- 4.97] than those living in Bhuj [23.20 +/- 6.21]. Mean differences at 95% confidence interval for these timings were found to be 7.24, 7.28 and 21.78 respectively. In both the villages, females had lower mean timing scores than males but the difference was not statistically significant [P>0.05]. Chronic exposure to high levels of fluoride in water was observed to be associated with lower intelligence quotient

'Role of Early Second Trimester High Sensitivity C-Reactive Protein for Prediction of Adverse Pregnancy Outcome'.

A prospective cohort study was carried out to evaluate the role of early second trimester high sensitivity C - reactive protein for prediction of adverse pregnancy outcomes. Total 150 early second trimester primigravidae were analyzed for serum hsCRP level which was measured by immunoturbidimetry assay and followed till delivery. A statistically significant correlation was found between elevated serum hsCRP concentrations in early second trimester primigravidae and adverse pregnancy outcomes like preterm delivery and pregnancy induce hypertension (p<0.001). This study reveals that elevated serum hsCRP concentration observed in early second trimester primigravida could help to predict adverse maternal and fetal outcomes and if timely preventive prophylactic therapies are tried, would help to prevent morbidity and mortality due to pregnancy disorders.

Relationship of periodontal status and dental caries status with oral health knowledge, attitude and behavior among professional students in India / 国际口腔科学杂志·英文版

<p><b>AIM</b>To find the relationship of periodontal status and dental caries status with oral health knowledge, attitude, behavior, among professional students in India.</p><p><b>METHODOLOGY</b>In a cross sectional study, a total of 825 students (males: 577, females: 248) from six professions were surveyed using a self administered structured questionnaire including 41 multiple choice questions and the WHO Oral Health Assessment Form (1997). The data was analyzed using the SPSS version 13.0 to perform the Student's t-test, ANOVA test, Scheffe's test and Chi-square test, linear regression analysis.</p><p><b>RESULTS</b>The mean percentage scores of the students for knowledge were 53.25 +/- 15.05; for attitude 74.97 +/- 20.48; and for behavior 59.09 +/- 18.77. The percentage of students with calculus score was found to be significantly high (43.8%). The percentage of professional students with DMFT >4 was 14.1% and the percentage of students with decayed teeth was 46.2%. The regression analysis showed that the oral health behavior of the students was dependent on the attitude (P < 0.001), but showed no significant linear relation with the knowledge. Also, that the mean DMFT score was dependent on the oral health behavior (P < 0.05), but showed no significant relationship with the knowledge and attitude of the students. The periodontal status was independent on the knowledge, but showed a significant relationship with attitude and behavior of the students.</p><p><b>CONCLUSION</b>A positive attitude and adherence to good oral hygiene behaviors is associated with better oral health.</p>