Potential Use of Bischofia javanica as an Active Ingredient of Functional Foods and Cosmeceutical Products Possessing Hyaluronidase, Collagenase, Tyrosinase and Urease Inhibitory Effects / 日本補完代替医療学会誌

<i>Bischofia javanica</i> leaf extract exhibited inhibitory activities against hyaluronidase, collagenase, tyrosinase and urease, suggesting that it is useful as an active ingredient for functional foods and cosmeceutical products. In particular, its 50% inhibitory concentration for hyaluronidase was comparable to that of disodium cromoglycate, which is a well-known hyaluronidase inhibitor used as an anti-inflammation and anti-allergy agent. In addition, the extract also inhibited urease with the almost the same potential as acetohydroxamic acid, which is reported to suppress <i>Helicobacter pylori</i>-induced gastritis by inhibiting urease.<br>