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Indian J Physiol Pharmacol ; 2019 Apr; 2: 130-137
Artículo | IMSEAR | ID: sea-198929

RESUMEN

Introduction: There are a number of ways to assess cognitive functions. The two most important androutinely done tests are neuropsychological battery and event related potentials. The present study examinedthe relationship between conventional neuropsychological tests assessing various domains of cognition andan event related potential (P300).Methods: Subjects were 60 neurologically normal healthy adults 20-30 years old with no history of neurological,neurosurgical, or psychiatric disorders. We administered a neuropsychological test battery (Penn CNP)assessing reaction time, visual memory and logical reasoning and recorded event related potential, P300using auditory oddball paradigm in all subjects.Results: A correlation test was run and pearson’s analysis revealed that there was a positive correlationbetween reaction time on neuropsychological test battery and P300 wave latency. No relationship was foundbetween other tests on neuropsychological test battery and P300 wave characteristics i.e., latency oramplitude.Conclusion: We therefore conclude that P300 measurements cannot be replaced by neuropsychologicaltests or vice versa; rather, higher cortical functions should be evaluated by both methods.

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