RESUMEN
Background: The objective of the study was to clinically evaluate age‑related ‑ oral manifestations and co‑morbidities in different age groups of human immunodeficiency virus‑infected/acquired immune deficiency syndrome adults. Materials and Methods: A cross‑sectional study was conducted among 200 adult patients aged above 20 years at infectious diseases units, medical wards and ART centre of Gandhi Medical Hospital, Hyderabad. Oral manifestations were diagnosed according to the presumptive criteria of EC‑Clearinghouse Classification, and clinical data were retrieved from patient’s medical records. Chi‑square test was used for statistical analysis. Results: Men (72%) in the young age group of 21–30 years were commonly affected. Heterosexual mode of transmission was most common in all the age groups, and the overall distribution were statistically significant (P < 0.05). Most common oral findings seen in 21–30 years of age were depapillation (90%), hyperpigmentation (70% and 72%) in 31-40 and 41–50 years old and linear gingival erythema (68%) in above 50 years of age group. The various co‑morbidities included the recurrent bacterial and skin infections (64% and 62% respectively) in the younger age group. Renal and cardiac diseases with pulmonary tuberculosis (74%) were commonly observed in middle‑aged and elders. Conclusions: The underlying oral manifestations and co‑morbidities could become very important variables that must be taken into account in determining treatment efficacy or health policy.