RESUMEN
To correlate colposcopic findings with the results of cervical biopsy and to prove colposcopy as a valuable screening tool for the diagnosis of premalignant and malignant cervical pathologies. A quasi experimental study Study was conducted from January 2008 to April 2010 in the Department of Obstetrics and Gynecology, Railway Hospital Rawalpindi. The study population included three hundred women who attended the outpatient department of Railway hospital over a period of two years. All these symptomatic women between the ages of 30-60 years were recruited with one or more of the complaints of post coital bleeding, intermenstral bleeding, postmenopausal bleeding, recurrent vaginal discharge or abnormal Pap smear. The recruited women were examined by speculum, followed by pap-smears. Out of 300 women Pap smear of 200 women was abnormal and showed inflammatory lesions at three consecutive times. These ladies were booked for colposcopy. However, any other women whose reports showed dyskaryotic changes were immediately booked for colposcopy. Biopsies from abnormal areas were taken and sent for histopathology. The reports of cervical biopsy were then analyzed. Out of 300 women recruited, 200 showed positive Pap smear. 108[54%] symptomatic women showed normal epithelium, while 92 women [46%] had abnormal transformation zone changes. Cervical biopsy reports of 92 women with abnormal colposcopic findings, showed up chronic cervicites in 60 cases, miscellaneous cervical pathologies in 10 cases, no dysplasia in 10 cases and cervical carcinoma was diagnosed in 12 cases. The study concluded that colposcopy followed by cervical biopsy proved to be a valuable screening tool for the diagnosis of premalignant and malignant cervical pathologies
RESUMEN
To compare the efficacy and safety of misoprostol with a Foley's catheter and oxytocin for induction of laborator beyond term. Quasi experimental study. This study was carried out in the Department of Obstetrics and Gynaecology, Railway Hospital Rawalpindi from January 2008 December 2008. Hundred patients requiring induction of labor at or beyond term with bishop less than 5 were randomized by lottery method to receive oral misoprostol or a cervical Foley's plus oxytocin. Patients in the misoprostol group [Group A] received 50 microgram misoprostol at6 hourly interval fora maximum of 4 doses or until an adequate contraction pattern developed. Those in the Foley's group [Group B] had a Foley's catheter inserted in the cervix. Whereas oxytocin was administered intravenously by a standard incremental infusion protocol to a maximum dose of 36 milliunits/min. The mean induction delivery interval is 9.8 hours in group A while in Group B the mean induction delivery interval was 17 hours. Although all patients delivered in both groups within 24 hours but the mean induction delivery interval was prolonged in Foley's group as compared to misoprostol group. The neonatal outcome was comparable in both the groups. Oral misoprostol at the dose 50 microgram is better than Foley's group for induction of labor at term