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Genet. mol. res. (Online) ; 2(1): 77-91, Mar. 2003.
Artículo en Inglés | LILACS | ID: lil-417622

RESUMEN

The bacteria Escherichia coli has been widely employed in studies of eukaryotic DNA repair genes. Several eukaryotic genes have been cloned by functional complementation of mutant lineages of E. coli. We examined the similarities and differences among bacterial and eukaryotic DNA repair systems. Based on these data, we examined tools used for gene cloning and functional studies of DNA repair in eukaryotes, using this bacterial system as a model


Asunto(s)
Animales , Células Eucariotas , Escherichia coli/genética , Reparación del ADN , Secuencia de Bases , Clonación Molecular , Daño del ADN , Escherichia coli/enzimología , Genes Bacterianos , Modelos Genéticos
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