1.
Br J Med Med Res
;
2015; 5(10): 1255-1259
Artículo
en Inglés
| IMSEAR
| ID: sea-176091
RESUMEN
Aim: To study the prevalence of Down syndrome by conventional chromosome analysis and Gbanded karyotyping. Materials and Methods: A retrospective analysis was performed on the case records of2750 paediatrics patients, of which 682 cases of confirmed Down syndrome was recorded by G-banding karyotyping. Results: Non-disjunction was the most common type of abnormality followed by Robertsonian translocation and lastly mosaic in ratio of 92.2:7.0:0.73 respectively. Conclusion: Results suggest that advanced maternal age is classic risk factor attributed to the incidences of Down syndrome.