Inhibitory Effect of Chaga (Inonotus obliquus) on Tumor Promotion in Two-Stage Mouse Skin Carcinogenesis / 日本補完代替医療学会誌

Chaga (the sclerotia of <i>Inonotus obliquus</i>) has been widely used as a folk medicine in the treatment of cancer, cardiovascular disease and diabetes in Russia, Poland, and several Baltic countries. More recently, this herb has been assessed for its cancer-preventing activity. Using a mouse model of skin cancer, oral administration of Chaga was found to inhibit tumor promotion by 12-<i>O</i>-tetradecanoylphorbol-13-acetate following initiation with 7,12-dimethylbenz[<i>a</i>]anthracene in mouse skin.<br>