Age‑related – oral manifestations and co‑morbidities in human immunodeficiency virus‑infected/acquired immune deficiency syndrome adults in Hyderabad, India.

Background: The objective of the study was to clinically evaluate age‑related ‑ oral manifestations and co‑morbidities in different age groups of human immunodeficiency virus‑infected/acquired immune deficiency syndrome adults. Materials and Methods: A cross‑sectional study was conducted among 200 adult patients aged above 20 years at infectious diseases units, medical wards and ART centre of Gandhi Medical Hospital, Hyderabad. Oral manifestations were diagnosed according to the presumptive criteria of EC‑Clearinghouse Classification, and clinical data were retrieved from patient’s medical records. Chi‑square test was used for statistical analysis. Results: Men (72%) in the young age group of 21–30 years were commonly affected. Heterosexual mode of transmission was most common in all the age groups, and the overall distribution were statistically significant (P < 0.05). Most common oral findings seen in 21–30 years of age were depapillation (90%), hyperpigmentation (70% and 72%) in 31-40 and 41–50 years old and linear gingival erythema (68%) in above 50 years of age group. The various co‑morbidities included the recurrent bacterial and skin infections (64% and 62% respectively) in the younger age group. Renal and cardiac diseases with pulmonary tuberculosis (74%) were commonly observed in middle‑aged and elders. Conclusions: The underlying oral manifestations and co‑morbidities could become very important variables that must be taken into account in determining treatment efficacy or health policy.

Intraosseous mucoepidermoid carcinoma of the mandible - a rare case report

Introduction: Mucoepidermoid carcinoma (MEC) is the most common salivary gland malignancy. The majority of these tumors arises in the parotid and minor salivary glands but may rarely develop intraosseously. Primary intraosseous mucoepidermoid carcinoma (PIOC) of the jaw bones is an extremely rare malignant salivary gland tumor. Very few cases have been reported in the literature to date. Case report: The current manuscript highlights clinical and radiographic features of a rare case of PIOC in a 32 year old Indian female patient. Conclusion: All the dental practitioners should be aware of the protean features of central MEC. These lesions should be included in the differential diagnosis of unilocular and multilocular radiolucent lesions of the jaws. An early and accurate diagnosis is important so that the neoplastic transformation must be identified and treated effectively.