RESUMEN
Drug non adherence is one of the major problems in treatment of psychiatric patients which could increase the risk of relapse and re-hospitalization. The aim of this study is to determine factors associated with drug non adherence by patients with mood disorders after their discharge from hospital and assessment of relation between drug attitude and drug adherence. In this cohort, prospective, and descriptive study, 150 patients with mood disorders [major depressive disorder, bipolar mood disorder] at the time of discharge were assessed. For each patient, demographic information form and Drug Attitude Inventory [DAI-10] [persian translation] was completed at the time of discharge. Then all of the patients were monitored monthly until 6 months through telephone. In every follow up DAI-10 and drug use inventory [which consists of causes of drug non adherence] were completed. Finally relation between different variables and patient drug attitude with drug adherence were assessed. From all studied variables such as demographic factors, diagnosis, treatment factors, and drug attitude, only drug attitude had a significant relation with drug adherence. Patients' attitude toward drugs has a major role in drug adherence