Immunohistochemistry in toxocaral granulomas

Clean laboratory bred albino mice were used. Three mice of these were used for testing the infectivity of eggs. Twenty four mice were sacrificed at 3 weeks and 3 months, 12 each time. Immunohistochemical study which is a combination of immunological and pathological changes was performed to determine the differential population of inflammatory cells in the reaction produced to T. canis infection in early and late stages