Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
Artículo en Inglés | IMSEAR | ID: sea-152595

RESUMEN

A simple, precise, rapid, selective, and economic reverse phase high performance liquid chromatographic (RP-HPLC) method has been developed for the simultaneous estimation of Lopinavir and Ritonavir in marketed formulations. Chromatographic separation was achieved isocratically for the combination was done with a C18 column [ ODS UG column. 250mm× 4.5 mm] utilizing mobile phase of composition Acetonitrile and Phosphate buffer (60:40v/v, pH 3) the flow rate was 1.5ml/min and the eluates was monitored at 220nm. Lopinavir and Ritonavir were eluted with retention times of 2.1min and 4.0min respectively. The method was found to be linear over a range of 20-100 μg/ml for Lopinavir and Ritonavir. The method was validated according to the guidelines of International Conference on Harmonisation (ICH) and was successfully employed in the estimation of commercial formulations.

SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA