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Indian J Lepr ; 1988 Jul; 60(3): 363-73
Artículo en Inglés | IMSEAR | ID: sea-55221

RESUMEN

In the present work we report our studies on IgG separated from the serum of lepromatous patients and non-lepromatous leprosy cases using Laser Raman Spectroscopy. Striking spectral changes in LL cases have been observed in the following special regions: (a) the amide I and III, (b) the S-S and C-S stretching (c) the skeletal bending and (d) skeletal stretching regions. These changes indicate a decrease in the amount of beta-structure and a transition towards alpha-helical conformation.


Asunto(s)
Proteínas de Unión al ADN/sangre , Humanos , Inmunoglobulina G/análisis , Rayos Láser , Lepra Lepromatosa/sangre , Espectrometría de Masas , Conformación Proteica , Estereoisomerismo
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