Risk factors and determinants of pulmonary function impairments in chronic respiratory diseases in Ethiopia: A hospital-based cross-sectional study

Introduction: Chronic respiratory diseases (CRDs) are diseases of the lung airways and parenchyma. Globally, they are the leading causes of morbidity and mortality. This study aimed to characterize the common CRDs, along with their lung function and possible determinants in symptomatic patients attending Bishoftu General Hospital, Ethiopia. Methods: A cross-sessional study was conducted at the outpatient of Bishoftu Hospital, Ethiopia from June 2019 to March 2020. Consecutive adult patients aged 18 and above with CRDs (≥8 weeks) were recruited. Questionnaires were used to collect data on demographics, symptoms, diagnoses, and putative risk factors. Lung function was measured by spirometry. Result: A total of 170 participants were recruited, the majority 102(60.0%) were female. The mean age was 49 years (SD=16). The most common symptoms were wheezing in the last twelve months 156 (91.8%), cough 138 (81.2%), and severe exertional breathlessness 137 (80.6%). Thirty-nine (22.9%) were either active or passive smokers. Half of the patients (50.3%) were exposed daily to vapors, dust, gases, or fumes and 58 (34.3%) were exposed to biomass smoke. In total, 138 (81.2%) had a positive allergen skin prick test. Chronic bronchitis (49.1%) and asthma (36.1%) were the most common clinical diagnoses. Classification of lung function revealed 23 (15%) normal, 29 (19%) obstructive, 36(23.5%) restrictive and 61(39.9%) mixed patterns. Airflow obstruction was independently associated with increasing age (p<0.05), exertional breathlessness (p<0.001), previous history of asthma (p<0.05), BMI (p<0.05), and doctor-diagnosed chronic obstructive pulmonary disease (p<0.001) and asthma (p<0.05). Conclusion: This study shows a high burden of abnormal lung function in patients attending clinics because of CRDs symptoms. These findings support the critical need for spirometry services to determine lung abnormality in patients with chronic respiratory symptoms.

Can lessons from public health disease surveillance be applied to environmental public health tracking?

Disease surveillance has a century-long tradition in public health, and environmental data have been collected at a national level by the U.S. Environmental Protection Agency for several decades. Recently, the CDC announced an initiative to develop a environmental public health tracking (EPHT) network with "linkage" of existing environmental and chronic disease data. On the basis of experience with established disease surveillance systems, we suggest how a system capable of linking routinely collected disease and exposure data should be developed. The primary operational goal of EPHT has to be the "treatment" of the environment to prevent and/or reduce exposures and minimize population risk for developing chronic diseases. Thus, EPHT should be synonymous with a dynamic process requiring regular system updates to a) incorporate new technologies to improve population-level exposure and disease assessment, b) allow public dissemination of new data that become available, c) allow the policy community to address new and emerging exposures and disease "threads," and d) evaluate the effectiveness of EPHT over some time interval. It will be necessary to weigh the benefits of surveillance against its costs, but the major challenge will be to maintain support for this important new system.

A prática de vigilância epidemiológica tem tradição secular nos Estados Unidos, e dados sobre ambiente vêm sendo recolhidos pelas agências de proteção ambiental americanas há várias décadas. Recentemente o Centro de Controle de Doenças (CDC) anunciou nova iniciativa para desenvolver monitoramento de enfermidades crônicas associadas à questão ambiental. Com base na experiência em sistemas de vigilância epidemiológica, sugerimos um sistema capaz de articular a coleta de informações epidemiológicas com dados de exposição ambiental. O objetivo operacional desse monitoramento é o tratamento do ambiente visando prevenir ou reduzir exposição e minimizar riscos de a população desenvolver doenças crônicas. Essas doenças resultantes de múltiplos fatores não podem ser avaliadas apenas por dados rotineiros de vigilância. Assim, essa nova proposta precisa se apoiar num processo dinâmico de: a) incorporar novas tecnologias para avaliar o nível de exposição e de doenças associadas; b) disseminar dados acessíveis ao público; c) incorporar a comunidade para levantar exposições e ameaças; d) avaliar periodicamente a efetividade da nova proposta. É preciso saber os benefícios dos mecanismos de vigilância frente aos custos para dar suporte a esse novo sistema.