RESUMEN
Chronic myeloid leukemia is a myeloproliferative disorder caused by a clonal disturbance of the trunk cell and the accumulation of granulocytic series in the marrow, blood and other organs. We report a 63 years old male, carrier of a chronic myeloid leukemia whose clinical condition was complicated by the appearance of a T cell lymphoma. He was subjected to chemotherapy, that reduced the size of adenopathies and improved his general condition. Further studies are required to determine if there is a relationship between these two clinical entities
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Linfoma no Hodgkin/complicaciones , Leucemia Mielógena Crónica BCR-ABL Positiva/complicaciones , Esplenomegalia/diagnóstico , Esplenomegalia/tratamiento farmacológico , Linfoma no Hodgkin/diagnóstico , Linfoma no Hodgkin/tratamiento farmacológico , Busulfano/uso terapéutico , Leucemia Mielógena Crónica BCR-ABL Positiva/diagnósticoRESUMEN
Se presenta una experiencia de tratamiento con clozapina en 11 pacientes esquizofrénicos resistentes. Se discute la eficacia del tratamiento y sus efectos adversos, así como la metodología empleada
Asunto(s)
Humanos , Adulto , Esquizofrenia/tratamiento farmacológico , Clozapina/farmacología , Estudios Prospectivos , Resultado del Tratamiento , Clozapina/administración & dosificación , Clozapina/efectos adversosRESUMEN
We report a boy in whom an advanced Hodgkin's disease, nodular sclerosis variety was diagnosed at 5 yeras of age and treated with exclusive chemotherapy. After 16 years of remission, he presented with a relapsed of the disease with a different histological pattern and was subjected to chemotherapy (C-MOPP/AVB) and unilateral axillary irradiation, obtaining a complete remission of the disease. Four months later, the patients is asymptomatic and without evidences of relapse