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Objective To evaluate the effect of preoperative radiotherapy and postoperative brachy radiotherapy (POBRT) on patients with primary liver cancer(PLC). Methods 50 patients with PLC were randomly divided into 2 groups:(1)Radiotherapy group, 25 patients who underwent preoperative radiotherapy 14～17 days before hepatectomy and POBRT 3～10 days after hepatectomy ;(2)Control group,25 cases who underwent hepatectomy only. In radiotherapy group, before heptectomy, the single-dose 6Gy per time and 3 sessions were given to each patient. 3～6 ductus were placed for POBRT during operation,and 10Gy of POBRT per time and 2～4 sessions were given postoperatively. In control group,no radio cherapy was given before and after hepatectomy. Results In radiotherapy group, the cancer shrank significantly after preoperative radiotherapy (P
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To explore an ideal way of small vessel anastomosis in microsurgery. Anastomosis of both carotid arteries were performed in 20 rabbits. The artery on one side was anastomosed with anastomotic clips,with the contralateral artery,which was anastomosed with sutures,for comparison. The vessels were harvested 1 and 14 days after the operation and were evaluated with operating microscopy, light microscopy and electronic microscopy. The average anastomosis time for suturing was about 15 min, while for clipping was 2～5min. There was no difference in patency between the two techniques. Endothelialization at the anastomotic sites were both completed 14 days postoperatively. However, when anastomotic clips were used, there were no endothelial damage and foreign bodies inside the vessels.This experiment has confirmed that anastomosis with clips provides a very safe and easy way to perform anastomosis and could reduce the incidence of thrombosis.
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The clinical characteristics of 22 patients with painless subacute thyroiditis (PST) were analysed and compared with other cases with thyrotoxicosis in the same period. The results show that PST is a self-limited diseases. Correct diagnosis should be made as early as possible to avoid inappropriate treatment.
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Objective:To evaluate the effects of pioglitazone,a insulin sensitizing agent, on plasma endothelin levels in patients with type 2 diabetes. Methods:Type 2 diabetic patients( n =48) with moderate vascular complication, who were orally taking hypoglycemic agents:sulfonylurea and biguanides (metformin), were divided into pioglitazone group (group A, n =24) and placebo group (group B, n =24) by the rule of random and double blind. Healthy voluneers were taken as control(group C, n =20). Three months before and after treatment, fasting plasma endothelin levels and serum insulin levels were assayed by RIA. Results:(1) Before treatment, fasting plasma endothelin levels were higher in type 2 diabetic patients compared to control group( P