A biomechanical system that can apply fluid shear stress to osteoclast-like cells in vitro / 生物医学工程学杂志

On the basis of the well-established principles and techniques about flow chamber, we have designed and made a kind of parallel plate system to apply steady fluid shear stress to osteoclast-like cells etc. in vitro. Biocompatible rubber and metal clamping apparatus made of aluminium alloy are used to seal the flow chamber without changing its even height designed beforehand. The influence of hydrostatic pressure on cells is minimized by adjusting the glass slide and the fluid surface in the upper reservoir to the same horizontal plane. This system can be used to investigate the responses of osteoclast-like cells etc. to fluid shear force in terms of morphology, physiology or biochemistry.

3-Dimensional finite element analysis of single implant-supported prosthesis with three different occlusal designs / 生物医学工程学杂志

This study was directed at analyzing the stress distribution of the implant in three different models whose cusp inclinations are 45, 35, 25 degrees respectively; the aim was to improve the success rate of implant rehabilitation. The method of is 3-dimensional finite element analysis (3D-FEA) was adopted. A volunteer's mandible was scanned using helix computer tomography and then we got the data of the mandible's margin in digital instrument. ANSYS program files were prepared using these data. Three models were created, meshed, analyzed in computer. Stress concentration was located on the cortical bone around the neck of implant and apical area of implant. Among the three designs, 25 degrees inclination of cusp was appropriate and in such a situation Von Mises stress was minimal.