Topical action of Buriti oil (Mauritia flexuosa L) in myositis induced in rats

Abstract Purpose: To analyze the topical effects of Buriti oil (Mauritia flexuosa L.) in induced myositis in rats. Methods: Thirty six male rats divided into three groups: Control group (C), induced myositis group (MI) and induced myositis group reated with Mauritia flexuosa L. (MT). After inducing myositis with 1% acetic acid, was topically applied 0.5 ml of Mauritia flexuosa L.extract on the posterior region of the right gastrocnemius muscle in animals belonging to group MT, for 7 and 14 days. Results: The neutrophil number there was statistically significant difference, after 7 and 14 days, between groups C and MI (p <0.001) (p<0.01). The group MT there was a significant difference in relation to MI group in both experimental times with (p<0.001). The number of fibroblasts in the 14 days showed that when comparing the groups M and MT the differences were also significant (p<0.001). As for the DLL, in 7 days, there was a significant difference between group C and MI group (p <0.001). When considering the MT group, there was a significant difference in relation to the MI group (p <0.001). Conclusion: The extract of Mauritia flexuosa L. leaves lessened acute and chronic inflammation, increased fibroblast proliferation and reduced macroscopically edema.

Efeitos da Passiflora edulis S. no processo de cicatrização em queimaduras induzidas em camundongos / Effects of Passiflora edulis S. in the healing process burns induced in mice

Introdução: Queimaduras levam à destruição parcial ou total dos tecidos expostos. A Passiflora edulis S. trata inflamações cutâneas. Objetivo: Avaliar os efeitos do extrato da Passiflora edulis em queimaduras induzidas em camundongos. Métodos: 30 camundongos, divididos aleatoriamente em três grupos iguais: Controle (C), Queimaduras (Q) e Queimadura tratado com extrato da Passiflora edulis S. (QT) subdivididos em sete e 14 dias. A avaliação qualitativa se baseou na presença de células inflamatória, fibroblastos e organização das fibras colágenas e a quantitativa no programa Image J®, função "cell conter". Resultados: Houve redução no número das células inflamatórias e aumento no número de fibroblastos no grupo QT aos sete dias, em comparação com os demais grupos. Aos 14 dias observa-se uma organização das fibras colágenas e uma diferença significativa (p<0,001), do número de fibroblastos, quando se relacionam os grupos Q e QT. Conclusão: O extrato da Passiflora edulis S. acelerou o processo de reparo das queimaduras induzidas em camundongos.

Introduction: Burns lead to partial or total destruction of the exposed tissue. The Passiflora edulis S. treats skin inflammation. Objective: Evaluating the effects of the Passiflora edulis S. extract in burns induced in mice. Methods: 30 mice, randomly divided in three equal groups: Control (C), Burns (Q) and Burns treated with the Passiflora edulis S. extract (QT) split in seven and fourteen days. The qualitative evaluation was based on the presence of inflammatory cells, fibroblasts and organization of the collagen fibers and the quantitative was based on the Image J® program, function "cell counter". Results: A reduction of the amount of inflammatory cells and a raise on fibroblasts was noted on the QT group after seven days. After the fourteen days it was observed an organization of the collagen fibers and a significant difference (p<0,001) on the fibroblasts number when related to the Q and QT groups. Conclusion: The Passiflora edulis S. extract accelerated the repair process of the induced burns on mice.

The low-level laser on acute myositis in rats

ABSTRACT PURPOSE: To analyze the effects of the low-level laser therapy in the acute myositis induced in rats. METHODS: Twelve rats were subjected to bilateral ovariectomy for inducing osteoporosis. After surgery, they were divided into two groups: Ovariectomy-control group (G1, n=6), receiving 0.5 ml distilled water by gavage for 30 days, and Ovariectomy plus mastruz group (G2, n=6), receiving 0.5 ml of the hydroalcoholic extract of mastruz at 10% concentration (50mg) daily, for the same period. Then, the blood of the animals was collected for further biochemical analysis (liver function) and tibia and liver were removed for histological and histomorphometric analyses. RESULTS: In the MT group there was a statistic significant decrease in the number of inflammatory cells, related to the MI group (p<0.05), increase in the fibroblastic proliferation, when compared to groups C and MI related to MT group (p<0.01) and statistic significant edema regression (p=0.0400) in the MT group CONCLUSION: The low-level laser therapy was efficient in the reduction of the inflammatory process, increase of the fibroblastic proliferation and the reduction of the edema.

Estudo do creme de buriti (Mauritia flexuosa L.) no processo de cicatrização / Study of buriti (Mauritia flexuosa L.) cream in the healing process

Objetivo: Avaliar o efeito do creme de buriti (Mauritia flexuosa L .) na cicatrização de lesões cutâneas em camundongos. Métodos: Cinquenta e seis camundongos foram submetidos ao procedimento cirúrgico de exérese da pele na região dorsal. Após a cirurgia, os grupos foram tratados com solução fisiológica 0,9%, creme de buriti a 5% e a 10% e Fibrase®. Resultados: No sétimo dia, foi observada uma redução significativa da área da ferida nos animais tratados com creme de buriti 5% e Fibrase® em relação ao controle. Não foram observadas diferenças entre os grupos no 14º dia de tratamento. A análise histológica demonstrou a presença de tecido de granulação mais evoluído, fibras colágenas e fibroblastos nas amostras do creme de buriti a 5% e Fibrase a partir do sétimo dia de tratamento. Conclusão: O creme de óleo de buriti a 5% apresentou capacidade aceleração do processo de cicatrização.

Objective: To evaluate the effect of buriti (Mauritia flexuosa L.) cream on the healing of skin lesions in mice. Methods: Fifty-six mice underwent surgical procedure of excision of the skin in the dorsal region. After surgery, the groups were treated with saline 0.9%, buriti cream 5% and 10% and Fibrase®. Results: On the seventh day was observed a significant reduction of the wound area in the animals treated with cream buriti 5% and Fibrase® when compared to control. No differences were observed between groups on the 14 th day of treatment. Histological examination showed the presence of granulation issue more evolved, fibroblasts and collagen fibers in the samples buriti cream 5% and Fibrase® from the seventh day of treatment. Conclusion: The buriti cream 5% is able to accelerate the healing process.