Prevalence of Anti-HBcore Total and HBsAg among Health Care Workers in Public Hospitals, White Nile State, Sudan; 2013.

Background: HBV infection is an occupational disease where health care workers (HCW) are at high risk. Aim: To measure the sero-prevalence of Anti-HBcore Total and HBsAg among HCWs in Public Hospitals, White Nile State, Sudan; 2013. Methods: A cross-sectional, hospital- based study was conducted among health care workers in Public Hospitals in White Nile State, Sudan; 2013. A sample of 385 HCWs was selected using two stage cluster sampling. A pre-tested structured questionnaire was used. The HCWs signed the informed consent to fill the questionnaire and to draw 5 ml venous blood sample for HBV tests. Blood samples were investigated for Anti-HBcore Total. Positive blood specimens for Anti-HBcore Total were further investigated for HBsAg. Data was processed using statistical package for social sciences (SPSS), version 16. Descriptive statistics and non-parametric Z test for single proportion was used at 95% CL. Results: Out of 385 HCWs, 230 (60%) were positive for Anti-HBcore Total. Out of 230 HCWs, 62 (27%) were positive for HBsAg. Prevalence for Anti-HBcore Total and HBsAg is significantly different from the expected values, P=0.001 Conclusion: Sero-prevalence of Anti-HBcore Total and HBsAg is high among HCWs in Public Hospitals in White Nile State, Sudan.

Past Medical History of Blood Transfusion; Surgical Operation; Vaccination against HBV; Cutter Scar and Tattoo; and HBV Infection Among Health Care Workers in Public Teaching Hospitals in Khartoum State; Sudan

Background:Infection with the hepatitis B virus (HBV) can lead to a range of clinical illnesses. Hepatitisis a general term meaning inflammation of the liver and the most common cause is infection with a variety of different viruses. All of these can cause an acute disease and symptoms lasting several weeks includingyellowing of the skin and eyes; dark urine; extreme fatigue; nausea; vomiting and abdominal pain.Aim:This study examined the prevalence of sero-epidemiologic markers of hepatitis B virus (HBV)among health care workers (HCWs) in Public Teaching Hospitals in Khartoum State; in the year 2004. Itattempted to determine the relation of the past medical history of blood transfusion; surgical operation;vaccination against HBV; cutter scar and tattoo with HBV infection among HCWs.Method:The study is anobservational; cross sectional; facility-based study. It was conducted on stratified two-stage cluster randomsample of 843 subjects. The study followed multivariate analytical techniques; using Multiple DiscriminantAnalysis (MDA); and some non-parametric tests using Chi-square test results:Among the 843 subjectstested for all HBV markers (Anti-HBc; HBsAg; HBsAb; and HBeAg); the prevalence of Anti-HBc; HBsAg;HBsAb; and HBeAg was found to be 57 (CI95:53-60); 6 (CI95:4.0-8.0); 37 (CI95:34-40) and 9 (CI95:7-11) respectively. The prevalence rate differs according to past medical historyfactors. Significant association of past medical history factors was found with seroprevalence of HBsAgmarkers (P0.05). No significant association was found with any of the past medical history factors forseroprevalence of Anti-HBc and HBeAg and HBsAb markers (P0.05).Conclusion:Tattooing and itsduration had shown significant result with HBsAg