Electrophoretic distribution of serum proteins in humans with brucellosis

Human brucellosis was diagnosed positive when Rose Bengal antibody test was I/ 160 or above in 116 patients [32 males and 84 females] ranging in age between 10-60 years The results indicated a significant decrease in albumin fraction and a marked rise in globulins, mainly the gamma fraction, and consequently a decrease in albumin/globulin ratio from 1.005 to 0.730. Such alterations were associated with a rise in antibody titres