RESUMEN
Health effects of Radio frequency waves have been raised because of the gradual increase in usage of cellphones, and this Usage of cellular phones is associated with alterations in various body systems including thecentral nervous system. The impact of radiation emitted from mobile phone on experimental animals stillunclear and contradictory and there is limited reviewed work of Mobile phones radiation effect on blood-brainbarrier and therefore; the purpose of this work was to review the possible effects of mobile phone radiation onblood-brain barrier from findings in the literature on tissues in human and experimental animals.This review is grounded on the various scientific published articles, journals and textbooks accessed on linefrom January 2010- November, 2011 and summarize the main results of studies of mobile phone radiationimpact on blood-brain barrier permeability published until 2009. Accordingly, number of studies relating toelectromagnetic field emitted by cell phones over a wide range of frequency is used, depending on a number ofelectromagnetic field parameters, duration of exposure and Specific absorption rate values.Several authors have reported that electromagnetic exposure alters blood-brain barrier permeability. On thecontrarily; other authors have reported differently in confirming these findings and more over it is also reportedthat mobile phone radiation-induced activation of cellular stress response might affect blood-brain barrierpermeability . Generally, the results of different studies conducted in experimental animals have revealed thatlong term exposure to cell phone radiation and at high or low Specific absorption rate value enhances increasedpermeability of the blood-brain barrier.