1.
Indian J Exp Biol
; 1994 Aug; 32(8): 562-4
Artículo
en Inglés
| IMSEAR
| ID: sea-58259
RESUMEN
Cyclophosphamide induced a depletion in liver glutathione (GSH) and high rate of lipid peroxidation. GSH depletion was evident from 20 min onwards and the maximum depletion was observed at 3 hr post treatment. Lipid peroxidation was significant only after the maximum depletion of GSH. Pretreatment with either MPG or WR-77913 individually, or in combination could prevent the depletion of GSH and induction of lipid peroxidation after cyclophosphamide treatment.
Asunto(s)
Amifostina/análogos & derivados , Animales , Ciclofosfamida/antagonistas & inhibidores , Femenino , Glutatión/metabolismo , Peroxidación de Lípido/efectos de los fármacos , Masculino , Ratones , Tiopronina/farmacología
2.
Artículo
en Inglés
| IMSEAR
| ID: sea-123901