Dengue encephalitis.

Encephalitis is an uncommon manifestation of dengue fever. Here we present a 4-year-old female child from northeastern India with dengue encephalitis. To our knowledge, this is the first reported case of dengue encephalitis from this region.

Symmetric peripheral gangrene of the lower limbs in a case of complicated falciparum malaria.

Association of symmetric peripheral gangrene (SPG) with falciparum malaria infection is a relatively uncommon clinical entity. Here we report a case of complicated falciparum malaria with SPG involving both lower limbs from the mid-calf downwards, probably due to antibody mediated vasculitis.

Emergency in malaria.

Malaria is still the most prevalent and devastating parasitic disease worldwide. In recent years drug resistance Plasmodium falciparum malaria has returned to most of the tropical countries of the globe with a vengeance. Due to various atypical manifestations the diagnosis has become confusing and hence the treatment delayed leading to various complications and increased mortality and morbidity. Patient presents with features of severe complicated malaria with multiorgan involvement in the form of malarial crisis needs emergency management in ICU. All fever cases with possible malaria should be investigated and to be treated with intravenous quinine/artimisinine pending confirmation of diagnosis. Any emergency situation that develops during treatment should be treated aggressively as medical emergency.

Transmission of malaria and its control in the northeastern region of India.

Let alone the eradication, malaria control itself has amounted to be a challenge, and is detrimental to the all round development of the northeastern region of India. Focal outbreaks are frequent taking heavy tool on human lives. Plasmodium falciparum is the predominant parasite species and is solely responsible for increased morbidity and mortality. The region contributes bulk of P. falciparum cases for the rest of India, and its proportions are increasing. Efficient vectors like Anopheles minimus, Anopheles fluviatilis and Anopheles dirus persistently support transmission of malaria. The present review gives a comprehensive account of the factors responsible for transmission of the disease with focus on vector bionomics, its prevention and control.

Primary orbital lymphoma.

Primary orbital lymphoma is a rare condition involving primarily the lacrimal glands. We present the second Indian case of right-sided primary orbital lymphoma in an elderly male who presented with the typical features and showed a good response to chemotherapy.

Clinical evaluation of halofantrine in acute malaria.

Fifty patients suffering from acute malaria were treated with 'Halofantrine Hydrochloride'. They were observed for 4 weeks. Clinical, haematological and biochemical parameters were assessed for evaluation of halofantrine in acute malaria, with special reference to its effectiveness, tolerability and side effects.

Ramsay Hunt syndrome with aseptic meningitis.

A case of Ramsay Hunt Syndrome with characteristic vesicles on the lateral aspect of the left pinna, evidence of infranuclear palsy of the left 7th cranial nerve, associated with same sided loss of taste sensation in the presulcal area of the tongue and perceptive deafness without vestibular disturbances is reported here. The patient had evidence of aseptic meningitis.