Change of GH/IGF axis and the correlation between GH/IGF axis and protein metabolism in old people with pulmonary infection / 中国实用内科杂志

Objective To investigate the change of GH-IGF ax is and the correlation between GH-IGF axis and protein metabolism in old people w ith pulmonary infection.Methods Serum GH,IGF-Ⅰ,IGFBP-1,IGFBP-3,total protein,albumi n,prealbumin and transferrin levels were detected in 20 aged patients with pulmo nary infection and 12 controls.The patients were admitted to the department of g eriatrics and emergency from Jul 2002 to Jan 2003.Results (1)The level of serum IGF-Ⅰin old people with pulmona ry infection was significantly lower than the control(P