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ObjectiveTo explore the imaging characteristics and the clinical and pathological diagnosis of gliomatosis cerebri in order to raise the awareness of the disease.MethodsThe images of 26 patients with gliomatosis cerebri were analyzed retrospectively.ResultsEight patients were treated with partial excision and 18 patients got stereotactic biopsy.The radiography examination included the plain and enhanced scan of CT and MRI.Twelve patients received 1H magnetic resonance spectroscopy (MRS).The disease in all the patients involved at least two cerebral lobes.There were 22 cases whose CT and MRI manifestations showed that there were large-sheet symmetry low-density image in brain and slightly long T1 and long T2 abnormal signals.And the enhanced scan showed that 20 cases had no obvious enhancement,2 cases had slight enhancement.There were 4 cases with large-sheet asymmetry lesions and no enhancement in enhanced scan.1H MRS examination of 12 cases showed that choline( CHO )/creatine(Cr) and CHO/N-acetyl aspartic acid (NAA) increased,NAA/Cr decreased with different degree,and 8 patients had lactate peak.ConclusionsMRI is the first choice to diagnose gliomatosis cerebri.1H MRS is very helpful for the diagnosis and pathological classification of the disease.MRI combined with biopsy can give out a definite diagnosis.
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Objective To explore MRI features of spinal arachnoid cysts.Methods The MRI appearances of 20 cases with spinal arachnoid cysts proved by surgery and pathology were retrospectively analyzed.There were 8 male and 12 female,they were conventionally scaned by MRI,12 cases of them were added Gd-DTPA contrast-enhanced scan.Results There were one nearilemma cysts,5 extradural arachnoid cysts,6 subdural arachnoid cysts,8 sacral arachnoid cysts.The signal intensity of cysts were long T_1 and long T_2 similar to that of cerebrospinal fluid signals and no enhanced on contrast MRI.Conclusion MRI is the best method in diagnosing the spinal arachnoid cysts.Contrast-enhanced scan is helpful for diagnosing and distinguishing of spinal arachnoid cysts.
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Objective To study diagnostic value of MRI in the mitochondrial encephalomyopathy about children.Methods 16 patients of mitochondrial encephalomyopathy in children had been examinatd with MR,proved by patholigy and biochemical laboratory examinations from 1996 to 2000.All of informations were retrospectively analysed.Results Brain parenchymal lesions in all cases were low signal intensity on T 1-weighted and high signal imtensity on T 2-weighted images.16 patients with mitochondrial encephalomyopathe of children,9 patients of them had only the deep gray matter involved,4 patients had both the deep gray matter and the cerebral cortex involved simultsneously,2 patients had with involvement of cortex and subcortical white matter,1 patient had exclusitvely involvement of white matter.Conclusion The varied clinical and MRI findings are the characteristic of mitochondrial encephalomyopathy,MRI has better helping to the diagnosis of mitochondrial encephalomyopathy in children.
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Objective To explore MRI diagnostic value of intervertebral disc infection.Methods 10 cases of intervertebral disc infection proved by operation and pathology were restrospectively analysed.Results 15 intervertebral discs were invalved in 10 patients.Among them,lumbar vertebral discs were only invalved in 7 cases,lumbar and sacrum vertebral discs were in 3 cases simultaneously.The involved discs were long T 1 and long T 2 signal intensity in 8 cases equal T 1 and short T 2 signal intensity in 2 cases.The soft tissue around vertebral was involved.The involved discs and soft tissue were enhanced in varied degrees on Gd-DTPA contrast-enhanced scan in 6 cases.Conclusion MRI is of important value in diagnosis of vertebral disc infection.