RESUMEN
To investigate the seroprevalence of fasciolosis and the possible causes of differences between rural and city center. We undertook a multi-stage sampling analysis of data from Isparta, Turkey, between March and June 2004. Four hundred and fifteen individuals participants from Isparta center and 171 from Asagi Gokdere village were included in the study. Fasciola hepatica [F. hepatica] specific antibodies were analyzed using excretory-secretory [ES]-enzyme-linked immunosorbent assay [ELISA] method. Fasciola hepatica antibodies were detected as positive in 10 [2.4%] of 415 people whose sera were collected from the city center and 16 [9.3%] of 171 people from Asagi Gokdere village. The positivity rates between village and city center were found statistically significant. A statistical difference was noted for fasciolosis positivity between individuals who have ingested water cress and who have not. Fasciolosis was not detected in the individuals who used to wash vegetables with water containing vinegar. Most of the patients in this region reported consumption of uncooked or unwashed water cress. Watering channel is one of the major risk factors of fasciolosis. Therefore, it is essential to determine the watering systems in this region. Moreover, ES-ELISA would be useful in investigating the laboratory diagnosis of fasciolosis