A Case of Blue Nevus of Posterior Wall of Pharynx / 대한이비인후과학회지

Menalocytic nevi are benign localized pigmented lesions, which usually occur on the cutaneous surface of the body but rarely on the mucous membranes. It is comparatively easy to encounter pigmented lesions of the oral cavity, but the melanocytic nevi of the pharyngeal wall are extremely rare worldwide and, to the best of our knowledge, there is no reported case of melanocytic nevus arising from pharyngeal wall. We report a case of a pigmented lesion on the posterior wall of pharynx, which was microscopically confirmed as oropharyngeal blue nevus.

A Clinical Study of Acute Epiglottitis: Retrospective Review of 315 Patients in Korea / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Acute epiglottitis is a life-threatening condition that can result in airway obstruction. The present study reports clinical features, management and patient outcomes in an acute epiglottitis. SUBJECTS AND METHOD: Included in our retrospective study were 315 patients who were admitted with the diagnosis of acute epiglottitis between January 2006 and July to the department Otolaryngology-Head and Neck surgery, Hallym University Sacred Heart Hospital 2018. The diagnosis of acute epiglottitis was established by confirmation of inflamed epiglottis using laryngoscope or computed tomography. RESULTS: Among 315 patients, 89 cases (28%) and 83 cases (26%) were found in the fifth and fourth decades, respectively. The mean age of patients was 45.0±13.94 years. The male to female ratio was 1.33:1. A total of 75 patients (23.8%) had co-morbidities, with hypertension (13.6%) being the most common. Fever was relatively uncommon, whereas most patients complained of sore throat. Ceftriaxone was the most common empirical antibiotic regimen prescribed and the use of steroids did not affect the length of hospital stay. Nine patients required airway intervention, including eight who underwent endotracheal intubation and one emergency tracheostomy. In patients who need airway intervention, systolic blood pressure, body temperature, respiratory rate, heart rate, white blood cells and the proportion of dyspnea were significantly higher in comparison to the patients without airway intervention. CONCLUSION: Although acute epiglottitis often has nonspecific symptoms, it may lead to sudden dyspnea and unstable vital signs, so an in-depth understanding of this disease is needed.

A Clinical Study of Acute Epiglottitis: Retrospective Review of 315 Patients in Korea / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES@#Acute epiglottitis is a life-threatening condition that can result in airway obstruction. The present study reports clinical features, management and patient outcomes in an acute epiglottitis.SUBJECTS AND METHOD: Included in our retrospective study were 315 patients who were admitted with the diagnosis of acute epiglottitis between January 2006 and July to the department Otolaryngology-Head and Neck surgery, Hallym University Sacred Heart Hospital 2018. The diagnosis of acute epiglottitis was established by confirmation of inflamed epiglottis using laryngoscope or computed tomography.@*RESULTS@#Among 315 patients, 89 cases (28%) and 83 cases (26%) were found in the fifth and fourth decades, respectively. The mean age of patients was 45.0±13.94 years. The male to female ratio was 1.33:1. A total of 75 patients (23.8%) had co-morbidities, with hypertension (13.6%) being the most common. Fever was relatively uncommon, whereas most patients complained of sore throat. Ceftriaxone was the most common empirical antibiotic regimen prescribed and the use of steroids did not affect the length of hospital stay. Nine patients required airway intervention, including eight who underwent endotracheal intubation and one emergency tracheostomy. In patients who need airway intervention, systolic blood pressure, body temperature, respiratory rate, heart rate, white blood cells and the proportion of dyspnea were significantly higher in comparison to the patients without airway intervention.@*CONCLUSION@#Although acute epiglottitis often has nonspecific symptoms, it may lead to sudden dyspnea and unstable vital signs, so an in-depth understanding of this disease is needed.

Prognosis of Patients with Benign Vocal Fold Lesions after Laryngeal Microsurgery

BACKGROUND AND OBJECTIVES: This study aimed to evaluate patients' subjective and objective outcomes after laryngeal microsurgery for benign vocal fold (VF) lesions, and to identify usefulness of surgical treatment. MATERIALS AND METHODS: The authors reviewed the 102 patients medical records, retrospectively who received laryngeal microsurgery for benign VF lesions from January 2013 to August 2017. Subjective voice were measured using the Voice Handicap Index (VHI). Objective voice were recorded with Multi-Dimensional Voice Program (MDVP) just before surgery, and after at least 3 months of surgery. RESULTS: Benign VF lesions were categorized as VF nodule (n=34, 33%), VF Polyp (n=47, 26%), Intracordal cyst (n=15, 15%), Reinke's edema (n=6, 6%), and VF Papilloma (n=2, 2%). Post-operative voice assessment at VHI scores showed statistically significant reductions in all of functional, physical and emotional parts (p < 0.001). MDVP were showed significant improvement of Jitter (P=0.001), Shimmer (p < 0.001) and Noise to Harmonic Ratio (NHR) (p=0.001). CONCLUSION: Laryngeal microsurgery for benign vocal fold lesions is effective treatment with statistically significant improvement at subjective and objective vocal quality assessment.

A Case of Rhabdomyosarcoma in Pharynx / 대한이비인후과학회지

Rhabdomyosarcoma is a highly aggressive malignant tumor with an incidence of 1/500,000 children per year. It originates from mesenchymal cell to invade soft tissue, developing into a highly aggressive malignant tumor. Rhabdomyosarcoma consists of the following four pathologic groups-embryonal, botryoid, alveolar, and pleomorphic type. While head and neck is the most common site of the embryonal rhabdomyosarcoma, the pharynx is rarely reported as a primary site of rhabdomyosarcoma. Recently, the 5-year survival rate of rhabdomyosarcoma has been greatly increased by combining therapy with radical surgery, although it still has poor prognosis. We present a case of rhabdomyosarcoma in the pharynx.

Clinical Usefulness of Neck Ultrasonography in Peritonsillar Abscess / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Clinical differentiation of peritonsillar abscess (PTA) from peritonsillar cellulitis is sometimes difficult and physicians often rely on blind needle aspiration to locate abscess formation. According to previous studies, intraoral ultrasound is a useful, simple, and noninvasive technique that candifferentiate PTA from cellulitis in clinically equivocal cases, although it may cause some discomfort. The objective of this study was to establish a neck ultrasonographic technique that candifferentiate PTA from cellulitis in borderline cases and thereby to avoid unnecessary needle aspiraton. SUBJECTS AND METHOD: The study population included 44 patients (32 males and 12 females; age range 13 to 59 years) with clinically suspected PTA. These patientsunderwent neck ultrasonography examination before needle aspiration of abscess. RESULTS: On the basis of neck ultrasonography, 38 patients were considered as PTA and 6 as cellulitis. Neck ultrasonography was able to detect peritonsillar abscess in 94.7 per cent of the cases (sensitivity). The specificity of the test was 83.3 per cent, and accuracy was 79.1 per cent. CONCLUSION: Neck ultrasonography is a useful, simple, well-tolerated non-invasive technique that can be used to differentiate PTA from cellulitis in clinically equivocal cases.

Parotidectomy: Surgical Treatment for the Benign Parotid Tumor / 대한이비인후과학회지

No abstract available.

Effects of Preserving the Posterior Branch of the Greater Auricular Nerve at Parotidectomy on Postoperative Peri-Auricular Sensation / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: The posterior branch of the greater auricular nerve is a sensory nerve that serves the skin over the mastoid process and the postero-inferior region of the auricle. The greater auricular nerve is often sacrificed in parotidectomy, even though its posterior branch can be preserved. By cautious dissection of the greater auricular nerve it is possible to preserve the posterior branch in 69 per cent of the operations. However, the efficiency of this procedure is not clear. So, we have compared the patients whose nerve had been preserved with those sacrificed, to evaluate the validity of the posterior branch of greater auricular nerve preservation during parotidectomy. SUBJECTS AND METHOD: Thirty patients undergoing parotidectomy were divided into two groups. Fifteen patients underwent parotidectomy with preservation of the posterior branch of the greater auricular nerve (group A) and they were compared with fifteen patients who underwent parotidectomy with sacrificing the nerve (group B). Using questionnaire, we have researched about numbness, pain or other subjective symptoms on peri-auricular area after parotidectomy and the function of the nerve has been tested by two point tactile discrimination test and temperature sensitivity test. RESULTS: Postoperatively, twenty-nine patients felt lack of sensitivity, pain, itching or other symptoms. These symptoms recovered within 12 months, subjectively. However, in group B, permanent sensory loss was found in three patients. The two-point discrimination test revealed in group B, the decreased sensitivity on the operated side in comparison with the unoperated side (p=0.008). It also showed the decreased sensitivity on operated side in group B, compare with group A (p=0.012). CONCLUSION: From this study, despites of no significant difference on subjective symptoms, there was objective improvement on function of the greater auricular nerve. It seems reasonable to spare the greater auricular nerve during parotidectomy.

The Effectiveness of Sternocleidomastoid Muscle Flap in Preventing Frey's Syndrome Following Parotidectomy / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Frey's syndrome is one of the potential sequelae of parotidectomy. Various medical and surgical treatments have been used in attempt to avoid this embarrassing condition. Recently, interposing barriers between the overlying skin flap and the parotid bed, such as the sternocleidomastoid (SCM) muscle flap, have been used to prevent this condition. The purpose of this study was to evaluate the preventive impact of using this flap on the incidence of Frey's syndrome and to identify the degree of severity in this syndrome between the use of SCM flap and no muscle flap. SUBJECTS AND METHOD: 40 patients who underwent superficial parotidectomy from June 1996 to August 2003 were divided into two groups. One group had SCM flap reconstruction (n=20), and the other did not (n=20). A subjective clinical questionnaire and the objective Minor's starch test were used to evaluate the incidence of this syndrome. A grading system was used to divide Frey's syndrome into mild or severe Frey's syndrome to determine its severity. The test of Pearson-x2 was applied. RESULTS: The association between sweating, flushing, or pain and the use of the flap was not significant. Also, there was no significant association with Minor's starch test and the use of the flap. There was a significant association with mild Frey's syndrome and the presence of the flap (p=0.014). CONCLUSION: It would seem that the sternocleidomastoid muscle flap does not reduce the incidence of Frey's syndrome, but does decrease the degree of severity in Frey's syndrome.

A Case of Actinomycosis Arising in Parotid Gland / 대한이비인후과학회지

Actinomycosis is an unusual granulomatous infection caused by gram-positive organisms (Actinomycetes. israelii, A. naeslundii, A. odontolyticus, and A. viscosus). Depending on the involved anatomical region, actinomycosis is classified into three clinical forms: cervicofacial (the most common, 55%), thoracic, or abdominopelvic. It is still a rare disease constituting less than 1% of all infections and primary parotid actinomycosis is even more rare, indeed. Actinomycosis typically has a chronic, indolent course characterized by swelling and induration of the soft tissues and eventual spontaneous drainage through multiple sinus tracts. The sulfur granule defines the pathognomonic pathologic finding of actinomycosis, but it has been reported in only 40% of cases. Treatment of cervicofacial actinomycosis consists of: removal of the infectious source, such as an infected tooth; incision and drainage, ideally including irrigating drains, and appropriate use of antibiotics and surgery. Our case dealt with a 55-year-old female presenting a firm mass in right parotid area. She was treated with surgical excision and antibiotic treatment.

A Case of Acute Airway Obstruction due to Intracystic Hemorrhage of Thyroid Papillary Cancer / 대한이비인후과학회지

Thyroid papillary cancer is the most common type of thyroid cancer and the incidence rate is 70-80% of entire thyroid cancer. 10-year survival rate is more than 90%. It is mostly irregular marginated- hard mass but, may have cystic property. The most common clinical symptom is silent neck mass, but rapid growth or local invasion may develope the symptoms such as pain, hoarseness, dysphagia, hemoptysis and dyspena. With the 10% of invasion rate, it spreads to adjacent muscle, recurrent laryngeal nerve, pharynx, larynx, trachea, esophagus and spinal cord. We report a case of acute airway obstruction due to intracystic hemorrhage of thyroid papillary cancer which invades the retropharynx.

A Case of Pleomorphic Adenoma Arising from Nasopharynx / 대한이비인후과학회지

Pleomorphic adenoma is most frequently seen in the major salivary glands. Pleomorphic adenoma in minor salivary gland is relatively rare and can be found in palate, lip, buccal mucosa, tongue, oropharynx, nasal cavity, paranasal sinus, parapharynx as well as in the nasopharynx. Pleomorphic adenoma of nasopharynx is very rare, and only a few cases were reported both in neonates (congenital type) and adults (acquired type). We report the adult case of nasopharyngeal pleomorphic adenoma (Eustachian tube origin) with a review of literature.

A Case of Adult onset Fibromatosis Arising in Submental Region / 대한이비인후과학회지

The fibromatoses are histologically benign fibrous neoplasms arising from the musculoaponeurotic structures throughout the body. They are characterized as infiltrative, usually well-differentiated firm overgrowth of fibrous tissue and are locally aggressive. These rare lesions constitute only 0.03% of all neoplasms. Two-thirds of all fibromatoses arise from the anterior sheath of the rectus abdominis muscle. The majority of extra-abdominal fibromatoses originate from the shoulder and pelvic girdle musculature. Other sites include the extremities, the bowel mesentery, and the head and neck. Surgery is the first-line treatment for extraabdominal and abdominal wall fibromatoses. The aim of excisional surgery as primary treatment for aggressive fibromatosis is to obtain clear histological margin, but because of the infiltrative nature of the tumor, and multicentricity in some cases, the local recurrence rate is up to 90%. Recently, we have experienced a case of adult-onset fibromatosis arising in submental area. The lesion was excised and diagnosis was confirmed by histologic examination.

Sclerotherapy for Craniofacial Venous Malformation / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Venous malformations are one of the most common vascular anomalies, and are more frequently found in head and neck region. Various treatment options are available, and intralesional injection of sclerosant is the commonest primary treatment modality. We reviewed 20 cases of venous malformation treated with sclerotherapy at Seoul National University Hospital. MATERIALS AND METHODS: Twenty cases of venous malformation in head and neck were reviewed retrospectively, which had been managed with sclerotherapy from January 1991 to July 2001. The patients were treated at the department of otolaryngology-Head and Neck Surgery or plastic surgery of Seoul National University Hospital. Emulsion of Ethamolin and Lipiodol was used as a sclerosing agent. Some patients received surgical treatment after sclerotherapy. All of the patients received direct-puncture venography(Digital subtraction angiography) before sclerotherapy. Treatment results were evaluated by using MRI, angiography, or CT. If the reduction of volume of mass was more than 50 percent after sclerotherapy, we regarded the result as effective, if less than 50 percents, non-effective. Statistical analysis was done using SPSS10.0 for windows. RESULTS: Among twenty patients, there were eight males(40%), and twelve females(60%). Ages at the beginning of treatment ranged from six to thirty-eight years(mean age:20.6 years). The most common site of lesions was cheek(in 12 cases). Mass sizes(largest diameter) ranged from 2 cm to 20 cm. Nine cases were managed with both sclerotherapy and surgical excision, and eleven cases, only with sclerotherapy. Thirteen cases(65%) responded well to sclerotherapy(volume reduction>or=50%). There was no major complication. Tenderness, induration, swelling, and pain were reported as post-sclerotherapy complaints. Mild dyspnea occurred in one case, and the patient was managed at ICU shortly without fatal event. CONCLUSION: Sclerotherapy with or without surgical excision was an effective treatment modality for venous malformation, with minimal risk of major complications. There were no significant differences in the treatment results according to the initial size of the lesions.

Frequency and Distribution of Lymphocytes Related to Innate Immunity in Palatine Tonsils and Adenoids / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Palatine tonsils and adenoids protect the human body from various pathogens entering through the pharyngeal mucosa. Many studies have been performed for the specific immunity, but the innate immunity related to cell-mediated immunity has been rarely studied. Natural killer (NK) cells, CD5+ B lymphocytes, and gamma sigma T lymphocytes are the key mediators of natural immunity. The aim of this study was to investigate the role of lymphocytes related to the innate immunity property in these lymphoid tissues by examinig the frequency and distribution of these cells. MATERIALS AND METHODS: Palatine tonsils and adenoids were obtained from 12 children and 5 adults with idiopathic tonsillar hypertrophy. Immunohistochemisty was performed to examine the distribution of the CD5+ B lymphocytes, gamma sigma T lymphocytes and NK cells, and the flow cytometry was performed for the frequency of these cells compared with that of the patient's blood. RESULTS: On immunohistochemistry, CD5+ B cells were strongly stained mainly on the interfollicular and subepithelial areas of both the palatine tonsil and adenoid. But, gamma sigma T lymphocytes, and CD56+ cells were weakly stained on the interfollicular, epithelial, and subepithelial areas of both lymphoid tissues. Flow cytometry showed no difference in the frequency of CD5+CD19+ B cells and CD3+ gamma sigma T lymphocytes in these tissues compared to that of the blood. The frequency of NK cells of these tissues was much lower than that of the blood. And the frequency of CD3+ gamma sigma T lymphocytes of adults was lower than that of children in both the palatine tonsils and blood. CONCLUSION: In the palatine tonsils and adenoids, there were no active immune cells related to innate immunity, except for the CD5+ B lymphocytes in the non-stimulating state. And the innate immunity of the lymphoid tissues has possibility of association with the changing activity according to age.

Clinical Findings of Recurrent Respiratory Papillomatosis and Preliminary Results of the Adjuvant Therapy / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Recurrent respiratory papillomatosis (RRP) is difficult to treat because of its tendency to recur and spread throughout the respiratory tract. RRP is usually divided into two groups by age of onset. We aimed to investigate the different clinical courses between the childhood-onset and the adult-onset RRP and review the effects of the treatments. MATERIAL AND METHOD: We retrospectively reviewed 44 patients with RRP who had been treated in our hospital over the last 13 years. We compared the clinical courses and intersurgical intervals of childhood-onset RRP with those of adult-type and evaluated the effect of the alpha-interferon (local injection) by comparing preadjuvant average surgical interval with postadjuvant surgical interval with a review of the literature. RESULTS: Childhood-onset RRP was most often diagnosed between 1 and 4 years of age. It was more widespread and it recurred more frequently than adult-onset RRP, often involving the trachea and necessitating the tracheostomy. Therefore, more frequent surgical interventions were needed in childhood-onset RRP (2.81/year) than in the adult-type (1.14/year). Adjuvant therapy (local injection of alpha-interferon) was applied to 10 patients. Seventy-five percent of the 8 patients (2 were excluded due to short duration of F/U period) showed complete response (CR) or partial resopnse (PR) and only two patients did not respond to alpha-interferon at all. CONCLUSION: Childhood-onset RRP is more aggressive and widespread than its adult counterpart and intralesional injection of alpha-interferon seems to have a potential of a safe and effective adjuvant therapy for RRP.

Traumatic Hypopharyngeal-Cervical Esophageal Injuries / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Traumatic perforation in hypopharynx and cervical esophagus may be fatal, causing mediastinitis or sepsis. We present six cases of clinical experiences to outline diagnosis and management. MATERIALS AND METHOD: We retrospectively reviewed six patients with hypopharyngeal-cervical esophageal injury, over the period of recent two years. We summarized the method of diagnosis, treatment and clinical course with review of the literature. RESULTS: There were two cases of external blunt trauma, two cases of iatrogenic causes, and two cases of intraluminal injuries. The common clinical signs were painful neck swelling and fever. The five of six in routine X-ray showed air shadow in the neck or chest. The neck CT showed air or abscess in all six cases. The surgical drainage was performed in four cases. CONCLUSION: The diagnostic methods of hypopharyngeal-cervical esophageal injuries include chest X-ray, neck X-ray, Gastrografin(r) esophagography and CT after thorough history-taking and physical examination. CT was highly sensitive and important for decision of surgical management. Surgery is recommended if there is large perforation, abscess, mediastinal contamination or sepsis. In selective cases, non-surgical management is possible.

Telomerase Activity in Oral Leukoplakia Tissues / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: Telomeres are specialized structures found at the ends of eukaryotic chromosomes. Telomeres stabilize the chromosome and protect DNA from illegitimate recombination. Telomerase is a ribonucleoprotein, a RNA dependent DNA polymerase, and acts as a reverse transcriptase-like enzyme, which maintains telomere length by adding telomeric repeat units of TTAGGG to the telomeric end. These telomeric repeat units have been found only in cells with unlimited replicative potential such as sperm cells, immortalized cell lines and cancer tissues, but not in normal somatic cells. Telomerase is believed to be characteristic of and may be the best indicator of cell immortality. This study was performed to indentify the role of telomerase activity in the multistep carcinogenesis of oral squamous cell carcinoma. MATERIALS AND METHODS:We performed a telomeric repeat amplification protocol assay in 10 oral leukoplakia, 5 tongue cancers and 10 normal oral mucosa tissues. RESULTS: All the five tongue cancer tissues showed telomerase activity. Although telomerase activity was detected in 9 of 10 oral leukoplakia tissues and in 9 of 10 normal oral mucosa tissues, the activity of telomerase was low compared to that of cancer tissues by semiquantitative analysis. CONCLUSION: These findings suggest that telomerase maybe play a key role in multistep carcinogenesis of oral malignancy. Telomerase activity was detectable in normal oral mucosa with renewal activity suggested that this enzyme might be an indicator of cell proliferation.

Follicular Carcinoma of the Thyroid Gland / 대한이비인후과학회지

BACKGROUND: Follicular carcinoma of the thyroid is less common than papillary carcinoma and so with a few clinical data. OBJECTIVES: We performed this study for the purpose of getting further understanding and more supporting idea for diagnosis and treatment of follicular carcinoma. MATERIALS AND METHODS: Four hundred thirty patients with thyroid tumors were treated from 1991 to 1995. Twenty two patients were histopathologically proved as follicular carcinoma. All but one without treatment were reviewed retrospectively. RESULTS: Of the 430 patients, 382(88.8%) were malignant and 48(11.2%) were benign. In malignant tumors, 317(83.0%) were papillary carcinoma and 22(5.8%) were follicular carcinoma. Fine-needle aspiration cytology(FNAC) was performed in 17/21 which revealed malignancy only in 7 patients. Total thyroidectomies were performed in 18 patinets;12 patients had completion thyroidectomies. Cervical lymph node metastases presented in 3 patients and distant metastases were detected in 6 patients. According to the AMES risk group, 9 patients were in low and 12 patients were in high risk group. CONCLUSION: Follicular carcinoma of the thyroid reveals higher rate of distant metastases and lower accuracy of fine-needle aspiration cytology and frozen section biopsy. Therefore, the more aggressive treatment should be considered in high risk group after confirmation of distant metastases through careful evaluation.

A Clinical Analysis of Neck Masses / 대한이비인후과학회지

OBJECTIVE: We studied the clinical manifestations and charicteristics of the neck masses for taking the correct diagnosis. MATERIALS AND METHODS: In 1995, 403 patients were admitted and treated with neck masses at department of otolaryngology-head and neck surgery, Korea Cancer Center Hospital and analyzed retrospectively. The diagnosis was confirmed by radiological(CT, MRI, Ultrasonograph, etc) and histopathological(fine-needle aspiration cytology, incisional or excisional biopsies, and surgical procedures) studies. RESULTS: Ten cases(2.5%) were below 15 year-old age group and there were 4 cases of congenital masses, 3 cases of inflammatory masses, 2 cases of benign neoplasia, and 1 cases of malignant neoplasm. One hundred thirty-one cases(32.5%) were between 16 and 40 year-old age group and there were 7 cases of congenital masses, 33 cases of inflammatory masses, 31 cases of benign neoplasia, and 60 cases of malignant neoplasia. Two hundred sixty-two cases(65.0%) were above 41 year-old age group and there were 6 cases of congenital masses, 16 cases of inflammatory masses, 31 cases of benign neoplasia, and 20 cases of malignant neoplasia. Above 41 year-old age group, the malignant neoplasia were frequent. In all cases, the malignant neoplasia were frequent(67.0%) and among these primary malignant neoplasia were 118 cases and metastatic malignant neoplasia were 152 cases. In 17 cases of congenital masses, thyroglossal duct cyst was 7 cases and branchial cleft cyst was followed. In 52 cases of inflammatory masses, tuberculous lymphadenitis was the most(27cases) and reactive lymphadenitis was followed. In benign neoplasia, adenomatous goiter was the most(47cases) among 64 cases. CONCLUSION: Malignant neoplasia was 67.0%(270/403) of the neck masses and among these metastatic tumors was 56.3%(152/270). In women congenital masses was the most and then inflammatory masses and benign tumors were followed but in men malignant tumors were the most. After 5th decade, malignant neoplasia were frequent(79.8%) and neck masses in old age-patients were suspicious for the malignancies.