The effect of repeated chemotherapy on the prevalence and intensity of Ascaris lumbricoides and Trichuris trichiura infection.

The prevalence and intensity of intestinal nematode infections were assessed during 3 anthelminthic interventions in an urban community in Malaysia. The prevalence levels of Ascaris lumbricoides at Interventions 1, 2 and 3 were 30.6%, 18.9% and 15.5%, respectively and the mean intensities were 1.9, 0.75 and 0.81 worms per person. For Trichuris trichiura, the prevalence levels at Interventions 1, 2 and 3 were 46.9%, 21.6% and 15.7%, respectively. The mean intensities for T. trichiura at Interventions 1, 2 and 3 were 3.30, 0.92 and 0.07 worms per person. No gender-related prevalence and intensity were observed for the two geohelminths in this community. Prevalences and intensity had convex age profiles. Although repeated chemotherapeutic intervention reduced both prevalence and intensity levels, intensity was a more sensitive indicator than prevalence. The results indicate that age-targetting treatment at school children of 7-12 years of age would be an appropriate strategy for this community.

A community-based study of gastrointestinal helminth and protozoan infection in Western Jamaica

A study of gastrointestinal parasitic infection was conducted in four communities in the Parish of Westmoreland, Jamica. All blood smears (n=1,025) werw negative and 63,7% of stool specimens (n=696) contained ova/cysts of one or more of 7 helminth and 9 protozoan spcecies. Trichuris and Giardia were the most prevalent species. Prevalence was markedly age-dependent, with infection occuring most commonly in children. It is concluded that gastreointestinal parasitic infections persist at intensity and prevalence levels likely to have a significant impact on community health