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Journal of Veterinary Science ; : 215-222, 2013.
Artículo en Inglés | WPRIM | ID: wpr-104696

RESUMEN

Thirty-one dogs with patellar luxation (grades 2 and 3) were categorized into three groups. Group 1 (G.1; n = 12) had sodium hyaluronate (SHA) intra-articularly injected into the stifle joint that received surgery. Group 2 (G.2; n = 10) received SHA twice: first after surgery and then 1 week later. Group 3 (G.3; n = 9) served as a control, without injection. Blood was collected before injection and then once a week for 4 weeks after injection for evaluation of chondroitin sulfate (CS-WF6) and hyaluronan (HA). The results revealed significantly (p 0.05) was observed in serum biomarkers between G.1 and G.2. In conclusion, intra-articular injection with SHA after joint surgery may improve homeostasis of the joint, retarding the process of OA.


Asunto(s)
Animales , Perros , Femenino , Masculino , Análisis Químico de la Sangre/veterinaria , Sulfatos de Condroitina/metabolismo , Relación Dosis-Respuesta a Droga , Ensayo de Inmunoadsorción Enzimática/veterinaria , Ácido Hialurónico/administración & dosificación , Inyecciones Intraarticulares/veterinaria , Osteoartritis de la Rodilla/tratamiento farmacológico , Rodilla de Cuadrúpedos/cirugía , Viscosuplementos/administración & dosificación
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