A prospective study for weight changes associated with pregnancy

BACKGROUND: This prospective study was performed to evaluate factors influencing weight changes pregnancy period and pospartum period. METHODS: A total of 195 women followed by prenatal care of the department of OBGY at Ajou University hospital, Suwon, Korea, between march, 1998 and march, 2000. Parity, activity, alcohol, smoking, age of menarche, and age of first and last pregnancy were recorded for prenatal information. Anthropometric measurements was checked at regular visits until 6 weeks after delivery and by telephone call at 6 months and 1 year postpartum. RESULTS: Mean age was 30.1 years old and mean body mass index was 21.1 kg/m2. Mean total weight gain during pregnancy was 13.6+/-4.63 kg and wide range was at third trimester. It shows that weight reduced gradually until 6 months postpartum but increased after that time. 1 year postpartum weight gain had high correlation(R=0.999, 0.01) with 6 months postpartum weight gain. Total pregnancy weight gain, weight retention on 6 week postpartum were not significantly correlated with 1 year postpartum weight gain. OR for becoming overweight on 1 year postpartum(> OR =5.2 kg) with excessive rate of gain on 6 months postpartum(> OR =2.9 kg) was 5.41(95% CI 2.20 13.31) adjusted by multiple logistic regression analysis(age, activity level, parity). OR for becoming overweight on 1 year postpartum with excessive rate of Total pregnancy weight gain(> OR =13.6 kg) was 4.48(95% CI 1.84 10.89) by multiple logistic regression analysis. CONCLUSION: 1 year postpartum weight gain had the correlation with only 6 months postpartum weight gain.

Treatment of Infectious Endophthalmitis

Endophthalmitis is a rare but catastrophic complication of intraocular surqeries and penetrating injuries. In spite of advances in diagnosis and therapy, the overall prognosis for recovery of useful vision has been regarded as poor. We experienced eight cases of endophthalmitis and performed vitrectomy combined with intravitreal antibiotics. Four(50%) had a final isual acuty of 0.2 or better. Vitrectomy was performed in cases of advanced intraocular inflammation, and intraocular lens was removed for suspected fungal endophthalmitis or to facilitate performance of a vitrectomy. A sample of vitreous, diluted by the irrigating solution, was passed through a disposable membrane filter system and inoculated into the culture media. Modification of therapy after initial broad spectrum antibiotics was based on the culture results and clinical responses. Repetitive intraocular antibiotic injections or reoperation were performed in severe cases.