RESUMEN
Background: The prevalence of obesity is increasing globally and one of the important factors associated with obesity is thought to be thyroid dysfunction. The objective of the present study was to find the incidence of subclinical hypothyroidism in overweight and obese individuals and to assess the relationship between the TSH levels and anthropometric parameters.Methods: A cross sectional study was conducted among 100 adults attending the hospital selected by a systematic random sampling method. Standard protocols were used to assess the laboratory and anthropometric parameters. Written informed consent was taken from the subjects and institutional ethical clearance was obtained before starting the study. Results: Of the 42% males and 58% females who were studied, 24% of the subjects had a BMI more than 24.99. 6% and 2% of the study subjects were having subclinical hypothyroidism and hypothyroidism respectively. There was a significant association between hypothyroidism and increased BMI values, waist circumference and waist hip ratio. Conclusions: A highly significant association was found between the serum TSH levels and the Body Mass Index, Waist circumference and Waist Hip ratio. The mean TSH levels were higher in the obese when compared to normal subjects.
RESUMEN
Background: Hypertension is one of the known cardiovascular risk factors. Several epidemiological studies have found an association between various anthropometric indicators and hypertension. The present study was conducted to investigate the relationship between different commonly and uncommonly used anthropometric parameters, various biochemical parameters and hypertension in adults.Methods: A hospital based cross sectional study conducted among 300 adults aged 40 years and more, attending Medicine OPD of a tertiary care institution after obtaining their consent and permission from institutional ethical committee. Anthropometric measurements, blood pressure examination and relevant laboratory investigations were done.Results: Hypertension was seen in both obese and non-obese study subjects. BMI, waist circumference, neck circumference, sagittal abdominal diameter and CRP was higher in hypertensive males than normotensives and it was statistically significant. BMI, waist circumference, hip circumference, neck circumference, sagittal abdominal diameter and CRP had a positive correlation with systolic and diastolic blood pressure and it was found to be statistically significant.Conclusions: CRP, serum ferritin, sagittal abdominal diameter, hip circumference, waist circumference and neck circumference showed a positive correlation with both systolic and diastolic blood pressure, which means that WC and SAD can be used to get information about visceral obesity in an individual. This also suggests that decrease in intra-abdominal fat could decrease the blood pressure.
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A 60 year old nonsmoker, non-diabetic, normotensive farmer presented with 4 days history of fever, myalgia & headache. He had relative bradycardia, eye congestion, diffuse muscle tenderness and tender hepatomegaly at presentation. He developed subconjunctival hemorrhage on 3rd in-hospital day. His investigations showed thrombocytopenia, hepatic and renal dysfunctions. His leptospira serology was positive. He was treated with injection crystalline penicillin and supportive therapy. While on treatment, even though he did not have any known cardiac risk factors, except for his age & gender, he developed 3 paroxysms of atrial fibrillation on 5th - 7th in-hospital days, without hemodynamic instability. His cardiac markers and echocardiogram during the paroxysms were otherwise normal. He had uneventful recovery, remained in sinus rhythm and stable at follow-up. This paroxysmal atrial fibrillation may be a coincidence or attributed as unusual association of leptospirosis.
RESUMEN
Colorectal cancers have potential for lymphatic and hematogenous metastases. Surgery is the definitive treatment, but the prognosis can be improved with the addition of chemotherapy, radiotherapy or both. However, the incidence of recurrence, both local and distant, remains significant. Distant metastases occur most often in the liver and lung; however, metastases to bone, adrenals, lymph nodes, brain, skin and the oral region have been reported. Metastases to the oral region are uncommon and may occur in the oral soft tissues or jaw bones. The prognosis in such patients is usually very poor. We report a case of colorectal carcinoma with metastasis to the floor of the mouth. This is probably the first reported case of metastasis to the floor of the mouth in a patient with colorectal cancer