RESUMEN
There has been a growing interest in the use of porous alloplastic implants for reconstructive orbital surgeries. Porous polyethylene (medpor) and hydroxyapatite are two of the more popular and successful orbital implants that revolutionized orbital reconstructive surgery, However, due to its prohibitive costs the authors in cooperation with the Department of Science and Technology have explored the use of a locally manufactured low cost (P25) synthetic Bioceramic Porous Biphasic Calcium Phosphate as a prospective orbital implant material for orbital floor fracture reconstruction. This study aims to establish and demonstrate biocompatibility and bone grafting characteristic of porous biphasic calcium phosphate orbital implant in cats as well as its capability to induce and support bone growth at 1 and 3 months. The implant composition of 77 percent tricalcium phosphate and 23 percent hydroxyapatite analyzed by means of an x-ray diffractometer clearly demonstrates its similarity to bone. 12 orbits of 6 cats underwent orbital plate implantation. Gross, radiographic, histological and histomorphometric examinations were done for the specimens at 1 & 3 months post-operatively. Evidence of lamellar bone deposition, vascularization without any signs of infection, inflammation, and resorption were observed in 6 out of 6 orbits in 1 month and 6 out of 6 at 3 months. Histomorphometric evidence shows bone-implant ratio of 30 percent deposition at 1 month and 50 percent deposition at 3 months. Porous biphasic calcium phosphate, an inexpensive orbital implant alternative has proven to have physiological bone induction as well as bone conduction properties. It is biocompatible, allows vascularization and is resistant to resorption. (Author)
RESUMEN
Difference in endocrine features between men and women supports a biological hypothesis in affective disorders among women. Studies done showed high probability that mood changes in associated with hormonal alterations, particularly that of estrogen and progesterone. There are cyclic morphological changes occurring in the female reproductive system in response to these hormones. The cytohormonal maturation index (CHMI) is used to evaluate the female hormonal milieu. A differential of the three types of cells is expressed as percentages of the parabasal (P), the intermediate (I), and the superficial (S) cells, in that order. Predominance of the intermediate cells reflect high levels of progesterone, and the superficial cells that of estrogen. This study aims to compare the correlation of CHMI with ovulatory phase between women of reproductive age with affective disorder and normal control; and to compare the CHMI of the two groups. Eight women of reproductive age (mean age = 29.62 +/- 7.95), diagnosed to have affective disorders and having an episode of mania/hypomania or depression, underwent Paps smear. Written consents were obtained. LMP and PMP were obtained to determine the current ovulatory phase. The control group is composed of seven women of same age group (mean age = 29.29 +/- 6.65) having no manifestations of any psychiatric illnesses. Paps smear was performed by a Gynecology Resident. A Pathology Resident blinded to the study reviewed the slides for CHMI. Fishers exact I test and Mann-Whitney U test were utilized. A p value of 0.05 was considered as statistically significant. There is a significant difference in the proportion of agreement between the ovulatory phase and the CHMI between the two groups (p=0.045). However, there is no difference in the percentages of progesterone and estrogen between the two groups (p=0.247 and 0.452, respectively).