RESUMEN
Qinling is a treasury of medicine with abundant resources of herbs. Due to the goal of enriching teaching contents, quality of teaching and creating a Chinese materia medica teaching system. Based on the Qinling plant gene database, our education team presents a series of innovative thoughts, such as multidisciplinary contact, inheriting and carrying forward the folk medicine, attaching importance to the practical application of herbs in Qinling and theory with practice to enrich teaching contentsand creating Shanxi characteristic teaching system of Chinese materia madica.That makes a contribution to raise the level of teaching in modern traditional Chinese medicine and promote the development of medicine in Shannxi.
RESUMEN
Objective To investigate the expression and its significance of BMI-1 gene in leukemia patients.Methods BMI-1 gene level was assessed by reverse transcription polymerase chain reaction (RT-PCR)in acute leukemia patients,chronic myeloid leukemia(CML)patients,chronic lymphoblastic leukemia(CLL)patients,and bone marrow mononuclear cells(BMMNC)as normal controls,as well as leukemia cell line K562.The expression of BMI-1 gene in leukemia and the relationship was explored.Results The expression of BMI-1 gene was positive in leukemia cell line K562.but negative in 10 controls as well as in CLL.The BMI-1 gene was expressed in 15.4% of CML patients and 47.1% of AL patients.The positive expression of BMI-1 gene in CML-CR was significandy lower than that in CML-BP (P＜0.05).Conclusion BMI-1 gene was over expressed in leukemia patients,and may be related to curative effect of the disease.It may be used for leukemia treatment targeting the provision of new sites.