Progress in the diagnosis of florid cemento-osseous dysplasia / 中华口腔医学杂志

Florid cemento-osseous dysplasia (FLCOD) is a rare, extensive bone metabolism disorder, which occurs only in the jaw bone. It is usually asymptomatic for a long time and discovered incidentally during a radiological examination. The characteristics of FLCOD in the initial stages are similar to those of periapical granuloma or jaw cyst, which may lead to misdiagnosis. After the lesion is mature, the imaging findings show that radiopaque with a thin radiolucent peripheral halo, which is crucial for the diagnosis of FLCOD, but other jaw lesions have similar imaging findings. Due to the poor blood supply of the lesion, the alveolar bone of root apices of vital teeth is slow to heal after trauma, increasing the chance of infection, which can lead to the osteomyelitis of the jaws and emerge sequestrum. This paper reviews the aspects of pathogenesis, clinical characteristics, diagnosis, differential diagnosis and treatment.

Analysis of the Test of Infant Motor Performance data from 642 infants with a postconceptual age of 38-58 weeks / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To investigate the differences between the Test of Infant Motor Performance (TIMP) data from the infants at 38-58 weeks of postconceptual age in three hospitals in Chongqing, China and the America norms, and to provide a reference for the introduction and application of TIMP in China.</p><p><b>METHODS</b>TIMP was used to assess 642 infants with 38-58 weeks of postconceptual age who visited the departments of preterm infants or child healthcare in the Second Affiliated Hospital of Army Medical University, Shapingba Maternal and Child Health Hospital in Chongqing, and Chongqing Maternal and Child Health Hospital between January and December, 2016. The assessment scores were analyzed and compared with the America norms.</p><p><b>RESULTS</b>The TIMP scores increased with the increasing postconceptual age, with 37±5 points in the 38-39week group and 83±12 points in the 56-57week group. All age groups had a significantly lower mean score than the America norms (P<0.001).</p><p><b>CONCLUSIONS</b>TIMP scores can reflect the motor performance in infants with various postconceptual ages. The TIMP scores from the infants with a postconceptual age of 38-58 weeks in three hospitals in Chongqing are significantly different from the America norms, suggesting that it is very necessary in China to establish the Chinese norms for assessing motor performance in infants using TIMP.</p>

Qualitative and quantitative comparative analysis of fatty acids in Cordyceps sinensis from different regions of Yushu prefecture of Qinghai Province / 中国药学杂志

OBJECTIVE: To establish a one-step esterification derivative analysis method for fatty acids in Cordyceps sinensis. and analyze and compare the composition and content of fatty acids of 12 samples from five counties of Yushu prefecture of Qinghai province. METHODS: Qualitative and quantitative analysis of fatty acids was performed by gas chromatography-mass spectrometry (GC/MS) in combination with comparison to reference substances, then the data was compared. RESULTS: Thirteen kinds of fatty acids of C14-C20 were found with a total amount of 79.81 - 160.20 mg · g-1. For a same sample, palmitic acid, oleic acid, and linoleic acid were the three kinds of fatty acids with the highest contents, the total content of which accounted for 92.81% -95.66% of the total 13 fatty acids. The proportion of unsaturated fatty acid was much higher than that of saturated fatty acids, and the ratio of UFA/SFA was 4.23-6.63. The fatty acids of 18 carbon and 16 carbon were the component with the highest amount and content, and the ratio of C18/C16 ranged from 4.04 to 6.19. Furthermore, the composition of the 13 fatty acids was basically consistent, while the content and proportion of the fatty acids varied greatly in samples from different origins. CONCLUSION: The method of fatty acids determination in Cordyceps sinensis set up by this research is simple, accurate, and reproducible, which is suitable for the fatty acids analysis in natural Cordyceps sinensis. The qualitative and quantitative data of the fatty acids could provide references for better recognition of the value of Cordyceps sinensis and further studies on its quality control.

Comparative study of fifteen kinds of nucleosides in Cordyceps sinensis from different origin of Yushu prefeuture, Qinghai Province / 中国药学杂志

OBJECTIVE: To establish an HPLC method for simultaneous determination of 15 nucleosides in Cordyceps sinensis, and investigate the differences in the composition and contents of these 15 nucleosides in 12 samples from 5 counties of Yushu prefecture, Qinghai province.

Simultaneous determination of gastrodin and eight nucleosides and nucleobases in Tibet cultured gastrodia elata by HPLC method / 中国中药杂志

This study aims to establish an HPLC method for simultaneous determination of gastrodin and eight nucleosides and nucleobases components in Gastrodia elata. The separation was carried out on an Agilent Zorbax Bonus-RP (4.6 mm x 250 mm, 5 μm) column with a methanol-(0.04% acetic acid) water solution gradient elution program at a flow rate of 1.0 mL x min(-1). The column temperature was 36 degrees C, and the detection wavelength was 254 nm. The volume of injection was 20 μL. The nine components including gastrodin, cytosine, uracil, cytosine, adenine, thymine, uridine, guanosine and adenosine were well separated. The calibration curve was well linear in the range of 2.04-262.00 mg x L(-1), 0.20-24.67 mg x L(-1), 0.18-23.75 mg x L(-1), 0.20-25.83 mg x L(-1), 0.20-26.67 mg x L(-1), 0.16-20.00 mg x L(-1), 0.22-27.71 mg x L(-1), 0.20-24.29 mg x L(-1), 0.24-30.58 mg x L(-1), respectively, and the correlation coefficient was between 0.998 9-0.999 9. The average recovery of gastrodin and eight nucleosides and nucleobases were 96.4%-99.6%, RSD less than 2.7% (n = 6). The contents of gastrodin in all the seven Tibet cultured Gastrodia elata samples were over 2 mg x g(-1). Further, all samples contain higher contents of adenosine, guanosine, uridine and cytidine compared to low contents of cytosine, uracil, adenine and thymine. The established method is accurate, reproducible and suitable for the determination of gastrodin and eight nucleosides and nucleobases comppnents in Gastrodia elata.

Effect of health education on blood pressure control in hypertensive population from a community of Wuzhou city / 心血管康复医学杂志

Objective:To study effect of health education on blood pressure control in patients with hypertension through community survey and perform health education.Methods:Residents from Datang street community re-ceived systematic sampling and questionnaire.A total of 490 patients with hypertension detected during census were regarded as subjects,and they were randomly divided into routine treatment group (n=240)and health education group (n=250).Health education group received health education,and effects were compared between two groups. Results:Compared with routine treatment group after intervention,there were significant rise in awareness rate of preventive and therapeutic knowledge [diagnostic value of hypertension (49.17% vs.58.40%),risk factors of hy-pertension (30.41% vs.58.00%),antihypertensive medication (58.75% vs.79.60%)]and control rate of blood pressure (23.33% vs.60.80%),and significant reduction in blood pressure [(147.68±13.97)/(89.30±12.43)mm-Hg vs.(143.57±13.53)/(85.73±11.54)mmHg]in health education group,P<0.05 or<0.01. Conclusion:Carry-ing out targeted health education possesses active significance for prevention and treatment of hypertension.

Establishment and application of Chinese Pediatric Evaluation of Disability Inventory norms in Chongqing, China / 中国当代儿科杂志

<p><b>OBJECTIVE</b>To establish the Chinese Pediatric Evaluation of Disability Inventory (PEDI) norms in Chongqing, China.</p><p><b>METHODS</b>PEDI (English version) was translated into Chinese and proof read by back-translation. A total of 1 140 children stratified by age were randomly selected from Chongqing and evaluated by the Chinese version of the PEDI. The obtained data were statistically analyzed.</p><p><b>RESULTS</b>Of 1 140 questionnaires, 1 075 (94.3%) were valid. The data showed that the raw and scale scores of PEDI increased with age, but the standard scores did not increase with age. The raw, scale, and standard scores on self-care and social function scales were significantly lower than American PEDI norms in some age periods (P<0.05), but the raw, scale, and standard scores on mobility scale were not significantly different from American norms (P>0.05).</p><p><b>CONCLUSIONS</b>The PEDI norms in Chongqing have been successfully established, and can be used to assess the daily function in children, judge the degree of daily function impairment, evaluate the effect of rehabilitation training, and make the rehabilitation plan for disabled children.</p>

Study on the genetic toxic effect of smoking on human oral mucosa / 实用口腔医学杂志

Objective:To study the genetic toxic effect of smoking on human oral mucosa,and the DNA damage of exfoliated oral mucosa cells.Methods:The DNA damage of exfoliated oral mucosa cells was investigated by single cell gel electrophoresis(SCGE)in 12 cases of malignant tumor,19 cases of benign tumor and 10 health controls.There were 24 smokers and 17 non-smokers among them.The tail length and frequency of comet cells were used to measure DNA damage.SPSS and SAS software were used for statistical analysis.Results:Malignant tumors had a longer tail length and higher frequency of comet cells than benign tumors and health controls,and the difference was statistically significant(P0.05).The DNA damage of exfoliated oral mucosa cells in smokers was more serious than that of non-smokers(P

Expression of P53 protein in oral tumor tissue in smoking and nonsmoking subjects / 实用口腔医学杂志

Objective:To study the relationship between smoking and P53 protein expression in oral tumor tissue.Methods:The expression of P53 protein in oral tumor tissue was detected in 22 smoking cases and 32 nonsmoking cases by immunohistochemical SP method. SAS software was used for statistic analysis.Results:The positive expression rate of P53 protein in smokers (90.91%) was higher than that in nonsmokers (46.88%,P0.05). Conclusion:Smoking may stimulate the mutation of p53 gene and play an important role in the carcinogenesis of oral tissues.

Digital subtraction angiography and selective external carotid embolization in the diagnosis and treatment of maxillofacial tumor / 实用口腔医学杂志

Objective:To study the feasibility of digital subtraction angiography(DSA) and selective external carotid embolization(SECE) in the diagnosis and treatment of maxillofacial tumor. Methods: DSA features, embolotherapy, clinical treatment and complications were investigated retrospectively in 22 cases diagnozed by means of DSA and treated with SECE. Results: After embolization, the bleeding was completely stopped in two cases with emergent hemorrhage, the tumor was shrunk in one case with central hemangioma in maxilla three weeks later and the bleeding in operation was reduced significantly. The tumor boundary was clear for tumorectomy in all the other cases. No recurrence was observed in 3-year-follow up. Conclusion:DSA and SECE are safe, optimal and effective in the treatment of maxillofacial tumour and hemorrhage.