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2.
Asian Pac J Allergy Immunol ; 1993 Dec; 11(2): 97-101
Artículo en Inglés | IMSEAR | ID: sea-36878

RESUMEN

A placebo-controlled, double blind, cross-over study of inhaled budesonide was carried out to examine its effectiveness in the treatment of chronic airflow limitation (CAL). Fourteen patients (11 males, mean age 66 years) with stable CAL received placebo treatment for four weeks followed by inhaled budesonide 400 micrograms BD for eight weeks. Response was assessed by measuring forced expiratory volume in one second (FEV1). There was no significant improvement in the overall spirometric measurements and symptom scores except a reduction in daily peak expiratory flow rate fluctuation (p < 0.05). However, individual patients showed significant increase in FEV1. Two patients (14%) had greater than 30% increase in FEV1 in response to inhaled corticosteroids. This response could not be predicted from history of allergy, skin test, bronchial challenge test, peripheral blood or sputum eosinophilia. We conclude that only a minority of patients with stable CAL may respond to inhaled budesonide. Nonetheless, patients who are symptomatic despite treatment with maximum doses of bronchodilators may have a trial of inhaled corticosteroids in order to demonstrate any additional benefit.


Asunto(s)
Administración por Inhalación , Administración Tópica , Aerosoles , Anciano , Antiinflamatorios/administración & dosificación , Pruebas de Provocación Bronquial , Bronquitis/tratamiento farmacológico , Broncodilatadores/administración & dosificación , Budesonida , Enfermedad Crónica , Método Doble Ciego , Enfisema/tratamiento farmacológico , Glucocorticoides , Humanos , Masculino , Persona de Mediana Edad , Pregnenodionas/administración & dosificación , Mecánica Respiratoria/efectos de los fármacos
3.
Southeast Asian J Trop Med Public Health ; 1992 Dec; 23(4): 702-4
Artículo en Inglés | IMSEAR | ID: sea-32132

RESUMEN

The prevalence of hypercalcemia in tuberculosis in Hong Kong and its occurrence in relation to the radiographic extent of disease were studied in 57 patients with sputum smear (n = 44) and/or culture positive (n = 13) pulmonary tuberculosis and in five patients with military tuberculosis prior to treatment. Only one (1.6%) patient had a corrected plasma calcium level above the reference range for our laboratory. There was a positive relationship between the corrected plasma calcium levels and the radiographic extent of disease (r = 0.37), p < 0.01). As the occurrence of hypercalcemia in tuberculosis is known to be influenced by the calcium intake, our finding of a low prevalence of "absolute" hypercalcemia in Hong Kong could be related to the low dietary calcium intake in these subjects.


Asunto(s)
Adulto , Anciano , Anciano de 80 o más Años , Calcio/sangre , Femenino , Humanos , Hipercalcemia/sangre , Pulmón/diagnóstico por imagen , Masculino , Persona de Mediana Edad , Albúmina Sérica/análisis , Tuberculosis Pulmonar/sangre
4.
Southeast Asian J Trop Med Public Health ; 1986 Mar; 17(1): 82-90
Artículo en Inglés | IMSEAR | ID: sea-34030

RESUMEN

Taeniasis is a major public health problem among the aboriginal populations on Taiwan, and is highly prevalent and wide spread in the mountain areas of 10 Counties. Over 27,000 cases of tapeworm infection are estimated influencing the health and economy in the endemic areas. A treatment of taeniasis with mebendazole and praziquantel followed by a re-treatment with atabrine has been done in the field trial, and confirmed that praziquantel is highly effective agent against tapeworm infection, but mebendazole is not. Based upon experiments reported here praziquantel in a single dose of 150 mg, and 450 mg are highly effective against taeniasis and hymenolepiasis respectively.


Asunto(s)
Adolescente , Adulto , Niño , Femenino , Humanos , Masculino , Mebendazol/uso terapéutico , Persona de Mediana Edad , Praziquantel/uso terapéutico , Quinacrina/uso terapéutico , Teniasis/tratamiento farmacológico
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