RESUMEN
Background: Hypothyroidism is a widespread thyroid problem, but there are no reports on the incidence and prevalence of hypothyroidism in this part of our country, that is western UP. Aims & Objective: The aim of the present study was to assess the prevalence of hypothyroidism in Meerut and nearby areas. Material and Methods: This retrospective hospital based study involved 4739 patients having undergone thyroid function assay, in the central clinical biochemistry laboratory of Subharti Medical College and its associated hospital. These patients were evaluated for thyroid hormonal assay-tri iodo thyronine (T3), tetra iodo thyronine (T4) and thyroid stimulating hormone (TSH) by Mini Vidas auto analyzer using enzyme linked fluorescent assay technique. Statistical analysis was performed by SPSS version 17 software. Results: Our study shows high prevalence of abnormal thyroid hormone levels (hypothyroidism was 8.2% & subclinical hypothyroidism was 8.4%) with female preponderance. Conclusion: The study has defined thyroid function status in thyroid patients of Meerut, Uttar Pradesh (U.P). Higher prevalence of hypothyroidism was observed in patients (especially females) in their second & third decade of life. The findings also supports the usefulness of screening of thyroid function compulsory after age of 30 years, for early detection and treatment to reduce the ill effects of thyroid dysfunctions.