RESUMEN
OBJECTIVE:To observe the clinical efficacy of Cistanche salsa tablets in treating endemic fluorosis. METHODS: A total of 137 cases were enrolled from endemic fluorosis disease-stricken area: 37 were assigned to receive Cistanche salsa tablets(1.2 g) po bid (trial group), and another 100 to receive Fenbid (300 mg) po bid as control for a treatment course of 4 weeks. The outcome measures included the total efficacy, time to take effect, adverse drug reaction and patients’ drug tolerance. RESULTS: In the trial group, the total effective rate was 86.49%, the time to take effect ranged from 7 to 15 days, and the ADR incidence rate was 35.14%, which was of significant difference as compared with control group.The patients in both groups had good drug tolerance. CONCLUSION: Cistanche salsa tablets are effective for endemic fluorosis and superior to Fenbid in efficacy.