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Braz. j. med. biol. res ; 53(7): e8943, 2020. tab, graf
Artículo en Inglés | LILACS, ColecionaSUS | ID: biblio-1132535

RESUMEN

This paper reports the development of a three-channel automatic speed-matching climbing training system that could train three rats at the same time for rehabilitation after an ischemic stroke. An infrared (IR) remote sensor was installed at the end of each channel to monitor the real-time position of a climbing rat. This research was carried out in five stages: i) system design; ii) hardware circuit; iii) running speed control; iv) functional testing; and v) verification using an animal model of cerebral stroke. The rehabilitated group significantly outperformed the middle cerebral artery occlusion (MCAo) sedentary group in the rota-rod and inclined plate tests 21 days after a stroke. The rehabilitated group also had a cerebral infarction volume of 28.34±19.4%, far below 56.81±18.12% of the MCAo group 28 days after the stroke, validating the effectiveness of this training platform for stroke rehabilitation. The running speed of the climbing rehabilitation training platform was designed to adapt to the physical conditions of subjects, and overtraining injuries can be completely prevented accordingly.


Asunto(s)
Animales , Ratas , Isquemia Encefálica/rehabilitación , Accidente Cerebrovascular/terapia , Terapia por Ejercicio/métodos , Rehabilitación de Accidente Cerebrovascular , Infarto de la Arteria Cerebral Media , Modelos Animales de Enfermedad
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