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Concerned literature on four kinds of andrographolide injections in recent 15 years were searched in CNKI, Wanfang and VIP databases. The adverse drug reaction(ADR) cases of Chuanhuning, Yanhuning, Xiyanping and Lianbizhi injections were classified and analyzed statistically, including a total of 194 articles and 3 479 cases. The ADR clinical characteristics and occurrence regularity of these four andrographolide injections were analyzed and compared from the gender, age, primary disease, emergence time of ADR, clinical manifestation, allergy history, dosage, prognosis and combined medication of the patients. It is useful to provide valuable references for rational use of these andrographolide injections in clinical practice.
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<p><b>OBJECTIVE</b>To study the effect of different concentrations of the extract of acanthopanacis senticosus on human sperm motility in vitro and to investigate its possible mechanism.</p><p><b>METHODS</b>By computer-assisted sperm analysis (CASA) system, we observed the effect of different concentrations of the extract of acanthopanacis senticosus on human sperm motility in vitro. The sperm obtained by masturbation and prepared by swim-up technique from 35 men with asthenospermia was incubated in different concentrations of the extract of acanthopanacis senticosus, and all the specimens were measured at 30, 60, 120 and 180 min respectively.</p><p><b>RESULTS</b>Different concentrations of the extract of acanthopanacis senticosus obviously improved the sperm motility of asthenospermia patients. The extract at the concentrations of 5 and 10 g/L increased the rate of motility (MOT), the percentage of progressive mobile sperm, the curvilinear velocity (VCL), the straight line velocity (VSL) and the average path velocity (VAP). Compared with the control group, the difference was significant (P < 0.05).</p><p><b>CONCLUSION</b>The extract of acanthopanacis senticosus can improve the sperm motility of asthenospermia patients in vitro and its optimal concentration is 10 g/L. The study may provide a new drug therapy for asthenospermia.</p>
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Humanos , Masculino , Astenozoospermia , Quimioterapia , Relación Dosis-Respuesta a Droga , Medicamentos Herbarios Chinos , Usos Terapéuticos , Eleutherococcus , Química , Glucósidos , Farmacología , Técnicas In Vitro , Fitoterapia , Motilidad EspermáticaRESUMEN
<p><b>OBJECTIVE</b>The paper was to evaluate the quality and characteristics of the Chinese Journal of Plastic Surgery(CJPS).</p><p><b>METHODS</b>With the database of Chinese Citation Index, the citation analysis was used to analyze the distribution of the cited original articles published in the CJPS from 2001 to 2005.</p><p><b>RESULTS</b>1045 papers were published during the period, and there were 530 (50.72%) cited by other researchers. The total frequency of citation was 1598, and each original article was averagely cited 3.02 times by other researchers. The published papers were cited by 289 journals and self-citing rate was 7.57%. The distribution of the most frequently cited authors covered 25 provinces, with Beijing, Shanghai, Shanxi and Guangdong Province in the lead in research work relevant to plastic medicine.</p><p><b>CONCLUSIONS</b>The Chinese Journal of Plastic Surgery has published high quality articles in the past five years. It is one of the most important information resource for the Plastic Surgery researchers and of the most important medical journals.</p>
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Bibliometría , Publicaciones Periódicas como Asunto , Cirugía PlásticaRESUMEN
Objective To study the development and research status of infectious diseases influ- ence in China and the academic influence of Chinese Journal of Infectious Disease.Methods Utilizing the literature metrology means,mainly based on《Chinese Journal Full-text Network Database》and《Chinese Citation Network Database》,statistics and analyses on the Cited Papers of Chinese Journal of Infectious Disease in 2000 to 2004 were made.Results The citation rate of 787 papers from 30 issues was 65.9%,citation frequencies in total were 2946 and the highest citation frequency was 245,the av- erage citation frequency was 5.7,and the rate of cited fund articles with total cited papers was 37.6% the total citation frequencies raised in the recent years and the average of influence factors was 1.281. Conclusion The Chinese Journal of Infectious Disease represents the highest level core periodical of infectious diseases in China and is one of the most important information resources in this research demesne.